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Official Full Name ALG11 asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) [ Homo sapiens ]
Background This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19.
Synonyms AI849156; alg11; ALG11_HUMAN; Asparagine-linked glycosylation 11; Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast); Asparagine-linked glycosylation protein 11 homolog; AW492253; B230397C21; GT8; KIAA0266; OTTMUSP00000022781; RGD1564725
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALG11-9571H Recombinant Human ALG11, His-tagged E.coli His
    Mouse ALG11-1542M Recombinant Mouse ALG11 Protein Mammalian Cell His
    Chicken ALG11-4477C Recombinant Chicken ALG11 Mammalian Cell His
    Zebrafish ALG11-7488Z Recombinant Zebrafish ALG11 Mammalian Cell His
    Zebrafish ALG11-8344Z Recombinant Zebrafish ALG11 Mammalian Cell His

    alg11 involved in several pathways and played different roles in them. We selected most pathways alg11 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with alg11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan biosynthesis MGAT1A; MAN1B1; ALG12; ALG2; DPM2; MGAT4B; ALG6; MAN2A2; MAN1C1; RPN2

    alg11 has several biochemical functions, for example, GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by alg11 itself. We selected most functions alg11 had, and list some proteins which have the same functions with alg11. You can find most of the proteins on our site.

    Function Related Protein
    GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity ALG11

    alg11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alg11 here. Most of them are supplied by our site. Hope this information will be useful for your research of alg11.


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