ALG10
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Official Full Name
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)
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Overview
This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. -
Synonyms
ALG10; asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); asparagine linked glycosylation 10, alpha 1,2 glucosyltransferase homolog (yeast); dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; derepression of ITR1 expression 2 homolog (S. cerevisiae); DIE2; FLJ14751; ALG 10; ALG10A; Alpha 1,2 glucosyltransferase ALG10 A; Alpha 2 glucosyltransferase ALG10 A; Alpha2 glucosyltransferase; Asparagine linked glycosylation 10 alpha 1,2 glucosyltransferase homolog (S. pombe); Asparagine linked glycosylation 10 alpha 1,2 glucosyltransferase homolog (yeast); Asparagine linked glycosylation 10 homolog (yeast, alpha 1,2 glucosyltransferase); Asparagine linked glycosylation protein 10 homolog A; Derepression of ITR1 expression 2 homolog; KCR1; Potassium channel regulator 1; alpha2-glucosyltransferase; alpha-2-glucosyltransferase ALG10-A; alpha-1,2-glucosyltransferase ALG10-A; asparagine-linked glycosylation protein 10 homolog A; asparagine-linked glycosylation 10 homolog (yeast, alpha-1,2-glucosyltransferase);
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | ALG10-460H | Recombinant Human ALG10 Protein, GST-tagged | Wheat Germ | GST |
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| Rat | ALG10-627R | Recombinant Rat ALG10 Protein | Mammalian Cell | His |
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| Rat | ALG10-283R-B | Recombinant Rat ALG10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | ALG10-283R | Recombinant Rat ALG10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Chicken | ALG10-3045C | Recombinant Chicken ALG10 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ALG10 Related Articles
ALG10 involved in several pathways and played different roles in them. We selected most pathways ALG10 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| N-Glycan biosynthesis | MGAT5;MGAT1;MAN1A2;ALG8;ALG11;FUT8;ALG2;ALG12;DPM3 |
| Metabolic pathways | ctaG;CBSB;PHYKPL;CYP8B1;GLUD1;HAL;CYP7A1A;ATP6V1B2;GFPT1 |
ALG10 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ALG10 itself. We selected most functions ALG10 had, and list some proteins which have the same functions with ALG10. You can find most of the proteins on our site.
| Function | Related Protein |
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ALG10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG10.
- Q&As
- Reviews
Q&As (19)
Ask a questionDefects may affect fertility and can cause problems such as genetic disorders.
ALG10 testing does not require fasting.
Defects are usually caused by mutations, loss or deletion of genes, which in turn affect the metabolism of protein glycosylation.
ALG10 is an important gene involved in protein glycosylation in human body and plays an important role in maintaining the normal function of human body.
ALG10 detection is mainly used to detect CDG-Ii and other related diseases.
The cost of ALG10 testing will vary due to different hospital and regional charges.
ALG10 deficiency has a familial genetic risk, and the risk of developing the disease depends on the family genetic history.
ALG10 detection can be interfered with by a number of factors, such as clinical symptoms, age, gender, diet, and so on.
This protein test results need to be interpreted and analyzed by a professional.
Testing needs to be performed by a professional clinical geneticist and laboratory technician.
ALG10 defects may cause CDG-Ii symptoms, including developmental delays, typical facial features, and low height.
ALG10 deficiency can be treated with targeted treatment for its clinical manifestations, such as symptom relief, rehabilitation, etc.
ALG10 defects can lead to the rare disease CDG-Ii, with symptoms including developmental delays, typical facial features, and low height.
ALG10 deficiency is a genetic disorder that can be passed on to future generations through genes.
ALG10 can be tested in the form of blood or oral swabs.
Testing does not require special preparation, but if a blood sample needs to be collected, the blood collection process needs to be completed under the guidance of a doctor.
The testing may help in the early detection of related diseases, so that targeted prevention and treatment measures can be taken, but often cannot prevent all related diseases.
ALG10 deficiency is a genetic disorder, so it may affect members of its family.
ALG10 testing is not a routine examination procedure and is usually done on the advice of a doctor.
Customer Reviews (4)
Write a reviewStrong reducibility.
Low requirements on storage environment.
Selective for strong cofactors of NADP(H).
At the same dose, the protein was highly expressed.
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