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Official Full Name asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
Background This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the;eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor;(dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with;congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALG12-461H Recombinant Human ALG12 Protein, GST-tagged Wheat Germ GST
    Human ALG12-9572H Recombinant Human ALG12, GST-tagged E.coli GST
    Chicken ALG12-3334C Recombinant Chicken ALG12 Mammalian Cell His
    Zebrafish ALG12-5710Z Recombinant Zebrafish ALG12 Mammalian Cell His

    alg12 involved in several pathways and played different roles in them. We selected most pathways alg12 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with alg12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan biosynthesis ALG12; RABGNT1; MGAT1B; MGAT4C; RPN1; B4GALT3; DPM1; MGAT2; MGAT5B; ALG1
    Metabolic pathways PDHB; GALNT2; GALNTL1; CECR1A; CYP2C37; ABP1; SCLY; PFKP; ackA; BAAT

    alg12 has several biochemical functions, for example, alpha-1,6-mannosyltransferase activity, dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity, mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by alg12 itself. We selected most functions alg12 had, and list some proteins which have the same functions with alg12. You can find most of the proteins on our site.

    Function Related Protein
    alpha-1,6-mannosyltransferase activity PIGB; GLT8D1; GTDC2; UGGT1; DPY19L4; B3GNT8; B3GNTL1; GALNTL4; B3GNT9-PS; POC1BL
    dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity ALG12
    mannosyltransferase activity ALG9; B3GNT8; ALG12; DPY19L4; PIGB; B3GNTL1; B3GNT9-PS; DPY19L1L; GTDC2; ZNF408

    alg12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alg12 here. Most of them are supplied by our site. Hope this information will be useful for your research of alg12.

    RPL13A; PRDX4

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