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Official Full Name asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
Background This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic.
Synonyms ALG6; asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 6 homolog (yeast, alpha 1,3 glucosyltransferase); dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; E230028F23Rik; Asparagine linked glycosylation 6; Asparagine linked glycosylation 6 homolog (S. cerevisiae alpha 1 3 glucosyltransferase); Asparagine linked glycosylation 6 homolog; Dolichyl P Glc:Man9GlcNAc2 PP dolichyl glucosyltransferase; Dolichyl P Glc:Man9GlcNAc2 PP dolichylglucosyltransferase; Dolichyl pyrophosphate Man9GlcNAc2 alpha 1 3 glucosyltransferase; Man(9)GlcNAc(2) PP Dol alpha 1 3 glucosyltransferase; MGC124652; My 046; My046; OTTMUSP00000008309; RP23-35D18.4; asparagine-linked glycosylation protein 6 homolog; Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase; dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase; dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase; dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase; asparagine-linked glycosylation 6 homolog (yeast, alpha-1,3-glucosyltransferase); asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase); CDG1C
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALG6-466H Recombinant Human ALG6 Protein, GST-tagged Wheat Germ GST
    Mouse ALG6-1549M Recombinant Mouse ALG6 Protein Mammalian Cell His
    Rat ALG6-630R Recombinant Rat ALG6 Protein Mammalian Cell His
    Chicken ALG6-6005C Recombinant Chicken ALG6 Mammalian Cell His
    Zebrafish ALG6-1117Z Recombinant Zebrafish ALG6 Mammalian Cell His

    alg6 involved in several pathways and played different roles in them. We selected most pathways alg6 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with alg6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan biosynthesis ALG2; ZNF408; DPAGT1; MAN1C1; ST6GAL1; MAN2A2; ALG5; MGAT5; ST6GAL2A; ST6GAL2
    Metabolic pathways PLCB3; DCTPP1; GATM; FH; AMD1; GUSB; IDH3G; PI4KA; POC1BL; SPS2

    alg6 has several biochemical functions, for example, dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity, glucosyltransferase activity, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by alg6 itself. We selected most functions alg6 had, and list some proteins which have the same functions with alg6. You can find most of the proteins on our site.

    Function Related Protein
    dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity UGGT1; B3GNTL1; GTDC2; B3GNT8; POMGNT2; DPY19L1; POC1BL; GLT8D1; GALNT18A; PIGB
    glucosyltransferase activity KDELC2; GLT8D1; DPY19L1; POMGNT2; KDELC1; GTDC2; 4931440L10Rik; PIGB; POGLUT1; B3GNT9-PS
    transferase activity DCLK3; UGT5C1; SMYD2B; PRKCBA; POLR2B; GSTM; GOT2B; MOCOS; ALPK2; CTU1
    transferase activity, transferring glycosyl groups UGT1AB; UGT2A5; PYGMA; GALNT18A; PNP6; ST3GAL5L; B3GALTLA; UGT5A2; PYGMB; UGT5A1
    transferase activity, transferring hexosyl groups B4GALNT1A; UGT2A5; UGT1A7C; UGT2A4; GBGT1; UGT5B4; UGT1B4; UGT1A5; 4931440L10Rik; ALG3

    alg6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alg6 here. Most of them are supplied by our site. Hope this information will be useful for your research of alg6.

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