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Official Full Name asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
Background This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of;the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins.;Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively;spliced transcript variants encoding different isoforms have been identified.
Synonyms ALG8; asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 8 homolog (yeast, alpha 1,3 glucosyltransferase); probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; MGC2840; 3-glucosyltransferase; AI447372; ALG 8; ALG8_HUMAN; Asparagine linked glycosylation 8 alpha 1,3 glucosyltransferase homolog; Asparagine linked glycosylation 8 homologyeast, alpha 1,3 glucosyltransferase; Asparagine linked glycosylation 8 homolog S. cerevisiae, alpha 1,3 glucosyltransferase; Asparagine-linked glycosylation protein 8 homolog; CDG1H; Dolichyl P Glc Glc1Man9GlcNAc2 PP dolichyl glucosyltransferase; Dolichyl P glucose Glc1Man9GlcNAc2 PP dolichyl alpha 1,3 glucosyltransferase; Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha 1,3 glucosyltransferase; Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; Gm1089; HUSSY 02; MGC74399; Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha 1,3 glucosyltransferase; Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1; HUSSY-02; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase; dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl-alpha-1,3-glucosyltransferase; asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase); asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALG8-467H Recombinant Human ALG8 Protein, GST-tagged Wheat Germ GST
    Human ALG8-8905HCL Recombinant Human ALG8 293 Cell Lysate HEK293 N/A
    Mouse ALG8-1550M Recombinant Mouse ALG8 Protein Mammalian Cell His
    Zebrafish ALG8-2415Z Recombinant Zebrafish ALG8 Mammalian Cell His

    alg8 involved in several pathways and played different roles in them. We selected most pathways alg8 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with alg8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan biosynthesis ALG14; ALG12; MGAT3A; RABGNT1; ALG13; ALG2; MAN1A2; STT3A; MAN1A; MAN2A1
    Metabolic pathways SAT1A.1; NT5C2; DNMT3B; BCKDHB; COX7C; PLCD1B; NDUFV2; MVK; CDA; CYP21A1

    alg8 has several biochemical functions, for example, alpha-1,3-mannosyltransferase activity, dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by alg8 itself. We selected most functions alg8 had, and list some proteins which have the same functions with alg8. You can find most of the proteins on our site.

    Function Related Protein
    alpha-1,3-mannosyltransferase activity GLT8D1; PIGB; ALG8; GALNT18A; 4931440L10Rik; GTDC2; B3GNT9-PS; POC1BL; UGGT1; B3GNTL1
    dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity POMGNT2; PIGB; UGGT1; ALG8; GTDC2; ALG6; 4931440L10Rik; B3GNT8; DPY19L1; POC1BL

    alg8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alg8 here. Most of them are supplied by our site. Hope this information will be useful for your research of alg8.

    RPS6KA5; NAE1; Atp2a2

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