ALG9

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ALG9

Official Full Name asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog
Background This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms ALG9; asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase) , asparagine linked glycosylation 9, alpha 1,2 mannosyltransferase homolog (
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALG9-468H Recombinant Human ALG9 Protein, GST-tagged Wheat Germ GST
    Human ALG9-8904HCL Recombinant Human ALG9 293 Cell Lysate HEK293 N/A
    Mouse ALG9-1551M Recombinant Mouse ALG9 Protein Mammalian Cell His
    Zebrafish ALG9-10898Z Recombinant Zebrafish ALG9 Mammalian Cell His

    ALG9 involved in several pathways and played different roles in them. We selected most pathways ALG9 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan biosynthesis ALG6; STT3B; ST6GAL1; MOGS; ALG5; ST6GAL2; ALG13; MAN1A; ALG8; MGAT3
    Metabolic pathways ACO1; GLCEA; LPIN1; PKLR; CHKA; CHIA.2; CHIA.3; NADSYN1; GOT2A; PRPS1A

    ALG9 has several biochemical functions, for example, dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG9 itself. We selected most functions ALG9 had, and list some proteins which have the same functions with ALG9. You can find most of the proteins on our site.

    Function Related Protein
    dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity ALG9; ZNF408
    dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity ZNF408; ALG9
    mannosyltransferase activity ZNF408; ALG9; GALNT18A; POC1BL; B3GNTL1; DPY19L1L; ALG12; PIGV; UGGT1; ALG1

    ALG9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG9.

    flhA; BHMT

    Coss, KP; Treacy, EP; et al. Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?. MOLECULAR GENETICS AND METABOLISM 113:177-187(2014).
    Barone, R; Fiumara, A; et al. Congenital Disorders of Glycosylation with Emphasis on Cerebellar Involvement. SEMINARS IN NEUROLOGY 34:357-366(2014).

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