Recombinant Human FASLG protein(Pro134-Leu281), His-tagged

• Cat.No.: FASLG-1396H
• Product Overview: Recombinant Human FASLG protein(Pro134-Leu281)(P48023), fused with a His tag at the N-terminus, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: N-His
• Protein length: Pro134-Leu281
• Form: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
• Bio-activity: Loaded Human FAS-Fc on Protein A Biosensor, can bind Human Fas Ligand-His with an affinity constant of 0.34 nM as determined in BLI assay.
• Molecular Mass: 17.7 Kda
• Endotoxin: < 1 EU/μg as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at ≤-70°C, stable for 6 months after receipt.
  Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
  Please minimize freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ]
• Official Symbol: FASLG
• Synonyms: FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1
• Gene ID: 356
• mRNA Refseq: NM_000639
• Protein Refseq: NP_000630
• MIM: 134638
• UniProt ID: P48023

Reviews

06/06/2021

The outstanding level of customer service adds extra reassurance and confidence in using the FASLG protein for my scientific investigations.

06/20/2018

the manufacturer of FASLG provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

08/28/2017

The FASLG protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

Q&As

Are there diagnostic tests that measure FASLG levels in clinical settings?

Yes, there are diagnostic tests that measure FASLG levels, which can provide insights into immune function and disease processes.

In what ways can the FASLG protein be targeted for therapeutic purposes?

The FASLG protein can be targeted for therapeutic purposes in cancer treatment and autoimmune disease management.

How is the FASLG protein involved in the pathogenesis of liver diseases?

Dysregulation of FASLG expression can contribute to liver injury and the progression of liver diseases such as hepatitis and liver fibrosis.

How does the FASLG protein contribute to the pathogenesis of inflammatory bowel disease?

Dysregulation of FASLG expression can impact intestinal immune homeostasis and contribute to the pathogenesis of inflammatory bowel disease.

What role does the FASLG protein play in organ transplantation?

FASLG is involved in the regulation of immune responses to transplanted organs, and its dysregulation can impact transplant outcomes.