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Recombinant Human FASLG Protein, His-tagged

Cat.No. : FASLG-244H
Product Overview : Recombinant human FASLG protein with His tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized
Molecular Mass : 17.7 kDa
Protein Length : 281
AA Sequence : MQQPFNYPYPQIYWVDSSASSPWAP PGTVLPCPTSVPRRPGQRRPPPPPP PPPLPPPPPPPPLPPLPLPPLKKRG NHSTGLCLLVMFFMVLVALVGLGLG MFQLFHLQKELAELRESTSQMHTAS SLEKQIGHPSPPPEKKELRKVAHLT GKSNSRSMPLEWEDTYGIVLLSGVK YKKGGLVINETGLYFVYSKVYFRGQ SCNNLPLSHKVYMRNSKYPQDLVMM EGKMMSYCTTGQMWARSSYLGAVFN LTSADHLYVNVSELSLVNFEESQTF FGLYKL
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens (human) ]
Official Symbol : FASLG
Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1;
Gene ID : 356
mRNA Refseq : NM_000639
Protein Refseq : NP_000630
MIM : 134638
UniProt ID : P48023

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there diagnostic tests that measure FASLG levels in clinical settings? 06/27/2019

Yes, there are diagnostic tests that measure FASLG levels, which can provide insights into immune function and disease processes.

In what ways can the FASLG protein be targeted for therapeutic purposes? 11/29/2018

The FASLG protein can be targeted for therapeutic purposes in cancer treatment and autoimmune disease management.

How is the FASLG protein involved in the pathogenesis of liver diseases? 09/17/2018

Dysregulation of FASLG expression can contribute to liver injury and the progression of liver diseases such as hepatitis and liver fibrosis.

How does the FASLG protein contribute to the pathogenesis of inflammatory bowel disease? 01/11/2018

Dysregulation of FASLG expression can impact intestinal immune homeostasis and contribute to the pathogenesis of inflammatory bowel disease.

What role does the FASLG protein play in organ transplantation? 01/17/2016

FASLG is involved in the regulation of immune responses to transplanted organs, and its dysregulation can impact transplant outcomes.

Customer Reviews (3)

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Reviews
06/06/2021

    The outstanding level of customer service adds extra reassurance and confidence in using the FASLG protein for my scientific investigations.

    06/20/2018

      the manufacturer of FASLG provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

      08/28/2017

        The FASLG protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

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