Recombinant Human FASLG Protein, GST-tagged
Cat.No. : | FASLG-3857H |
Product Overview : | Human FASLG full-length ORF ( AAH17502.1, 1 a.a. - 281 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 56.65 kDa |
AA Sequence : | MQQPFNYPYPQIYWVDSSASSPWAP PGTVLPCPTSVPRRPGQRRPPPPPP PPPLPPPPPPPPLPPLPLPPLKKRG NHSTGLCLLVMFFMVLVALVGLGLG MFQLFHLQKELAELRESTSQMHTAS SLEKQIGHPSPPPEKKELRKVAHLT GKSNSRSMPLEWEDTYGIVLLSGVK YKKGGLVINETGLYFVYSKVYFRGQ SCNNLPLSHKVYMRNSKYPQDLVMM EGKMMSYCTTGQMWARSSYLGAVFN LTSADHLYVNVSELSLVNFEESQTF FGLYKL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ] |
Official Symbol : | FASLG |
Synonyms : | FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1; |
Gene ID : | 356 |
mRNA Refseq : | NM_000639 |
Protein Refseq : | NP_000630 |
MIM : | 134638 |
UniProt ID : | P48023 |
Products Types
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FASLG-10553M | Recombinant Mouse FASLG Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FASLG-6324HCL | Recombinant Human FASLG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionYes, there are diagnostic tests that measure FASLG levels, which can provide insights into immune function and disease processes.
The FASLG protein can be targeted for therapeutic purposes in cancer treatment and autoimmune disease management.
Dysregulation of FASLG expression can contribute to liver injury and the progression of liver diseases such as hepatitis and liver fibrosis.
Dysregulation of FASLG expression can impact intestinal immune homeostasis and contribute to the pathogenesis of inflammatory bowel disease.
FASLG is involved in the regulation of immune responses to transplanted organs, and its dysregulation can impact transplant outcomes.
Customer Reviews (3)
Write a reviewThe outstanding level of customer service adds extra reassurance and confidence in using the FASLG protein for my scientific investigations.
the manufacturer of FASLG provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.
The FASLG protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.
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