Active Recombinant Human PTPN2 protein, His&GST-tagged

• Cat.No.: PTPN2-940H
• Product Overview: Recombinant Human PTPN2 protein(P17706-1)(Met1-Asn314), fused with His and GST tag, was expressed in Insect Cells.

Specification

• Source: Insect Cells
• Species: Human
• Tag: His&GST
• Form: Supplied as sterile 20mM Tris, 300mM NaCl, 10% glycerol, pH 8.0.Please contact us for any concerns or special requirements.Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Measured by its ability to dephosphorylate a phosphotyrosine residue in an EGF receptor 988-998 phosphopeptide substrate.The specific activity is > 20 nmoles/min/μg.
• Molecular Mass: The recombinant human PTPN2 (aa 1-314)/GST chimera consists of 551 amino acids and predicts a molecular mass of 64.4 kDa. It migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions.
• Protein Length: Met1-Asn314
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
• Official Symbol: PTPN2
• Synonyms: PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTPT; tyrosine-protein phosphatase non-receptor type 2; TC PTP; TCELLPTP; TCPTP; T-cell protein tyrosine phosphatase; PTN2; TC-PTP
• Gene ID: 5771
• mRNA Refseq: NM_001207013
• Protein Refseq: NP_001193942
• MIM: 176887
• UniProt ID: P17706