Recombinant Human DDX3Y cell lysate

• Cat.No.: DDX3Y-455HCL

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: DDX3Y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [ Homo sapiens ]
• Official Symbol: DDX3Y
• Synonyms: DDX3Y; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DBY, DEAD/H (Asp Glu Ala Asp/His) box polypeptide, Y chromosome; ATP-dependent RNA helicase DDX3Y; DEAD box protein 3, Y-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; DBY
• Gene ID: 8653
• mRNA Refseq: NM_001122665
• Protein Refseq: NP_001116137
• MIM: 400010
• UniProt ID: O15523
• Chromosome Location: Yq11
• Pathway: RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem
• Function: ATP binding; ATP-dependent helicase activity; DNA binding; RNA binding; helicase activity; hydrolase activity; nucleotide binding