ddx41

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ddx41

Official Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.
Synonyms DDX41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; probable ATP-dependent RNA helicase DDX41; AI324246; zgc:55896; 2900024F02Rik; AA958953; ABS; DEAD box protein 41; DEAD box protein abstrakt homolog; EC 3.6.1.-; fb92e02; MGC55896; MGC8828; wu:fb92e02; OTTHUMP00000161451; OTTHUMP00000223824; putative RNA helicase; DEAD-box protein abstrakt
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Ddx41-2508M Recombinant Mouse Ddx41 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human DDX41-2488H Recombinant Human DDX41 Protein, GST-tagged Wheat Germ GST
    Human DDX41-35H Recombinant Human DDX41 protein, GST-tagged E.coli GST
    Human DDX41-470H Recombinant Human DDX41 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DDX41-7005HCL Recombinant Human DDX41 293 Cell Lysate HEK293 N/A
    Zebrafish DDX41-11275Z Recombinant Zebrafish DDX41 Mammalian Cell His

    ddx41 involved in several pathways and played different roles in them. We selected most pathways ddx41 participated on our site, such as Cytosolic sensors of pathogen-associated DNA, IRF3-mediated induction of type I IFN, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytosolic sensors of pathogen-associated DNA TICAM1; LRRFIP1; IFI16; APPA; S100A12; DDX41; RIPK3; NLRP4; AGER; APPB
    IRF3-mediated induction of type I IFN NLRP4E; NLRP4C; IFI16; TREX1; NLRP4B; DDX41; NLRP4
    Immune System DYNC1LI2; SEC24A; LAIR2; KLC3; IRF9; MB21D1; CASP4; RACGAP1; LRRC41; ARIH1L
    Innate Immune System CD180; DEFA3; DEFB129; PELI2; CYLD; TAX1BP1; DEFB4A; HERC5; LAT2; SUGT1
    Regulation of innate immune responses to cytosolic DNA DDX41; TRIM56; NLRP4; NLRP4E; TREX1; NLRP4B; NLRP4C
    STING mediated induction of host immune responses IFI16; TREX1; NLRP4B; NLRP4C; NLRP4E; NLRP4; DDX41; MB21D1

    ddx41 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx41 itself. We selected most functions ddx41 had, and list some proteins which have the same functions with ddx41. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding KIF3C; ITM2C; P2RY4; IGF1RB; HIPK3A; MYO5C; CHKB; GALK2; CDK8; CDK5
    ATP-dependent RNA helicase activity DQX1; DDX51; DDX10; PL10; DHX16; DDX24; DDX17; CHST13; DHX36; DDX20
    DNA binding RCOR3; EMX3; ARNTL1B; ZFR; ZBTB24; ZNF2; MEIS1B; BRCA1; ZBED5; BANF1
    poly(A) RNA binding RPL6; TRIM56; SKIV2L2; CDKN2A; SRSF7; CELF2; RBM5; RAVER1; CS; RPS13
    protein binding TBCD; FTCD; LIN37; SSB; ECE1; USP22; IFNGR1; MCCC2; KRTAP12-2; ITGB2
    zinc ion binding QTRTD1; BRD1B; ADAM25; UBOX5; BRCA1; FHL3; MSL2B; PXNA; RP9; PRICKLE1A

    ddx41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx41 here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx41.

    SIAH1; CEP70; NKAP; ABL1; FYN; CRK; RNPS1; Ddx41; USP36; gltX; E2F3; DVL2; ANXA1; SNW1; Vps41

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