| Official Full Name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked |
| Background | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. |
| Synonyms | ATP dependent RNA helicase DDX3X; DEAD box protein 3 X-chromosomal; DEAD box X isoform; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; HLP2 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
ddx3x involved in several pathways and played different roles in them. We selected most pathways ddx3x participated on our site, such as Hepatitis B, RIG-I-like receptor signaling pathway, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx3x were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hepatitis B | NFKB1; NFATC4; HSPG2; CASP8; TP53; SMAD4; MAP2K1; PTK2B; IRF7; CREB3L2 |
| RIG-I-like receptor signaling pathway | IFNA2; IL12BA; TRAF3; CXCL8B.3; IFNA3; CASP10; MAPK11; IKBKG; MAPK12B; IFNW1 |
| TNF-alpha/NF-kB Signaling Pathway | TNIP1; TRAIP; COMMD1; TXLNA; NKIRAS1; ZFAND5; PFDN2; MARK2; TIFA; DAP |
| Viral carcinogenesis | PRKACA; CREB3L3; PIK3CD; MAD1L1; TBPL1; CCND2; HLA-C; EIF2AK2; PIK3R5; SYK |
ddx3x has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx3x itself. We selected most functions ddx3x had, and list some proteins which have the same functions with ddx3x. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | AMHR2; CSNK1E; Aatk; PRKAA2; RPS6KA3A; RBKS; CSNK2A2; UBE2D2; CSNK2A1; PRKACBB |
| ATP-dependent DNA helicase activity | ERCC3; XRCC6; CHD2; RTEL1; RECQL; CHST13; XRCC5; CHD1; DHX9; BLM |
| ATP-dependent RNA helicase activity | DDX25; EIF4A1B; ACTG2; DDX20; BAT1; DHX9; DDX42; DDX21; DHX15; DDX53 |
| ATPase activity | ABCB1A; MYH9; KIF9; NSFB; TOR1B; KIF21A; ATAD2; ABCA9; PSMC5; ATAD1 |
| CTPase activity | DDX3X |
| DNA binding | RX2; ORC4; MND1; HMGXB3; MNX2B; DMC1; LEF1; ISX; PPP1R10; PROX2 |
| GTPase activity | GSPT2; GNAI1; TUBA8L; RRAGC; RAB11B; RAB44; RHOB; ARL8A; ARHGDIB; RAC3 |
| RNA binding | ZNF74; RPL39L; PABPC1L2A; DDX11; AGFG1; HNRNPA1; RBFOX1L; ZNF385B; APOBEC3F; CPSF1 |
| RNA stem-loop binding | EPRS; DAZAP1; DDX3X; CPEB3 |
| eukaryotic initiation factor 4E binding | EIF4G1; DDX3X; ANGEL1; OTX2; HHEX; GRA; LARP1; EIF4EBP3L; EIF4EBP2; EIF4EBP1 |
| mRNA 5-UTR binding | LARP1; IGF2BP1; DDX3X; IGF2BP2; IGF2BP3; MRPS11; RPS14 |
| nucleoside-triphosphatase activity | DDX3X; ENTPD6; ENTPD8; NTPCR; ENTPD1; ENTPD3 |
| poly(A) RNA binding | RG9MTD1; FASTKD2; C1orf35; UBE2O; PYDC3; TRAP1; ABCF1; POP1; ZFP326; DHX16 |
| poly(A) binding | PABPC3; SYNCRIP; RBPMS; HNRPDL; DDX3X; HNRNPDL; ZC3H14; PABPC4; TIA1; EIF4A3 |
| protein binding | ILKAP; CAV1; ANLN; SHMT1; EPS8; CEP55; RNF19B; CCT4; SOX-2; TFAP2A |
| ribosomal small subunit binding | NPM1; ERAL1; MTIF3; NME1; CPEB2; DDX3X; DHX29; PTCD3; PIM1 |
| transcription factor binding | DIP2BA; PPID; SMARCD3; TFDP2; EPAS1; PELP1; ARNT; RNF222; SMARCA4; CDK9 |
| translation initiation factor binding | TRIM32; POLR2G; EIF3B; EIF3C; POLR2GL; EIF3BA; EIF2B3; EIF3M; LARP1; RPS24 |
ddx3x has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx3x here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx3x.
p27958-pro_0000037566; PABPC1
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy
