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Official Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
Synonyms ATP dependent RNA helicase DDX3X; DEAD box protein 3 X-chromosomal; DEAD box X isoform; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; HLP2
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • B2M
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDX3X-2222H Recombinant Human DDX3X Protein (2-662 aa), His-B2M-tagged E.coli His/B2M
    Human DDX3X-257H Recombinant Human DDX3X protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DDX3X-28325TH Recombinant Human DDX3X protein, GST-tagged Wheat Germ GST
    Human DDX3X-7007HCL Recombinant Human DDX3X 293 Cell Lysate HEK293 N/A
    Mouse Ddx3x-2506M Recombinant Mouse Ddx3x Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Chicken DDX3X-2498C Recombinant Chicken DDX3X Mammalian Cell His

    ddx3x involved in several pathways and played different roles in them. We selected most pathways ddx3x participated on our site, such as Hepatitis B, RIG-I-like receptor signaling pathway, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx3x were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hepatitis B MAP2K1; BAX; ATF4; TBK1; PCNA; IFNA17; GRB2; DDB2; PIK3CD; MAPK8
    RIG-I-like receptor signaling pathway MAPK11; RNF125; IL8L1; IFNA5; DDX3X; IL8L2; TRIM25; TBKBP1; DAK; IL-8
    TNF-alpha/NF-kB Signaling Pathway FAF1; TNIP1; RNF25; COMMD1; PFDN2; KIAA1967; USP2; CSNK2A1P; SMARCC2; TRAIP
    Viral carcinogenesis SKP2; PMAIP1; YWHAB; TRADD; HIST2H4; ATP6V0D1; SYK; GTF2H2; VAC14; HDAC1

    ddx3x has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx3x itself. We selected most functions ddx3x had, and list some proteins which have the same functions with ddx3x. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CSNK1G3; ACTR3B; TESK2; PLK3; CDC34; MYH9; SCYL2; DDX23; RAF1B; ERBB3B
    ATP-dependent DNA helicase activity WRN; FBXO18; RUVBL2; BLM; RTEL1; RECQL; G3BP1; XRCC6; DDX11; CHD4
    ATP-dependent RNA helicase activity FAM120B; DDX59; SUPV3L1; YTHDC2; DHX57; DDX18; DDX5; DHX29; DDX6; DHX9
    ATPase activity ABCA4; ABCD1; KIF7; PSMC1; KIF21A; ABCG2A; KIF9; VWA8; OLA1; ABCA5
    CTPase activity DDX3X
    DNA binding CDT1; EP300; ZFP30; TBR1B; ZNF395; TRIM27; BRIP1; MYO18A; SP110; ARID1AA
    GTPase activity GNA14; RASEF; RAP1B; GNG3; RAB39B; TUBB4A; DNM1A; ARL4C; DNM3A; RAB1A
    RNA stem-loop binding CPEB3; EPRS; DDX3X; DAZAP1
    eukaryotic initiation factor 4E binding HHEX; LARP1; EIF4G1; EIF4EBP2; GRA; EIF4EBP3L; OTX2; EIF4EBP1; ANGEL1; DDX3X
    mRNA 5-UTR binding RPS14; IGF2BP1; IGF2BP2; IGF2BP3; DDX3X; MRPS11; LARP1
    nucleoside-triphosphatase activity ENTPD8; ENTPD1; ENTPD6; DDX3X; NTPCR; ENTPD3
    poly(A) RNA binding H2-Q10; ANKHD1; KTN1; MANF; YARS; SRSF3; RBM8A; EIF5; HIST1H47; ZCCHC6
    protein binding STK25; TMEM43; LSM7; TCEANC2; TSPAN6; ZNF436; CASP2; C15orf23; PRSS21; HIST1H3D
    ribosomal small subunit binding DHX29; NPM1; ERAL1; NME1; DDX3X; CPEB2; MTIF3; PTCD3; PIM1
    transcription factor binding PPRC1; STAT3; APBB1; HDAC2; NLRP3; DOT1L; MLXIPL; PIANP; FIGLA; ARHGEF2
    translation initiation factor binding TBL2; EIF2B5; RPS24; CELF1; ZFP259; EIF3F; EIF2B4; POLR2D; LARP1; EIF3C

    ddx3x has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx3x here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx3x.

    p27958-pro_0000037566; PABPC1

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