| Official Full Name | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| Background | The lymphoma-associated Rck/p54 gene product is a member of the DEAD box protein/RNA helicase family which has a variety of functions including translation initiation, pre-mRNA splicing, and ribosome assembly. Overexpression of human Rck in a guinea pig c |
| Synonyms | DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
ddx6 involved in several pathways and played different roles in them. We selected most pathways ddx6 participated on our site, such as Deadenylation-dependent mRNA decay, Gene Expression, RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deadenylation-dependent mRNA decay | EIF4B; DCP1B; EIF4G1; EIF4EB; EXOSC8; NT5C3B; DCP2; LSM6; DDX6; EIF4A1 |
| Gene Expression | ZNF764; ZNF562; ZNF498; ZNF707; ZNF74; ADARB1A; DNMT1; SKI; WARS2; COX6B1 |
| RNA degradation | CNOT3A; DHX36; groL; EXOSC5; PABPC5; LSM2; CNOT8; LSM3; BTG3; ENO3 |
| mRNA decay by 5 to 3 exoribonuclease | LSM6; DDX6; DCP1B |
ddx6 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx6 itself. We selected most functions ddx6 had, and list some proteins which have the same functions with ddx6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | TARSL2; CKM; MVK; PRKCG; GMPS; DHX35; NTRK2; MTHFD1L; ACTC1; PCXB |
| ATP-dependent RNA helicase activity | DDX20; DQX1; DHX37; DDX21; DDX42; DHX30; DDX51; TDRD12; YTHDC2; DDX55 |
| RNA helicase activity | DHX16; RAD54B; SKIV2L2; DDX6; UAP1L1; DHX15; PRIM2; DHX9; CHST13; DDX24 |
| helicase activity | SMARCA5; RAD54L; BAT1; DHX58; DICER1; ATRX; PIF1; MOV10B.1; CHD6; ANXA1 |
| poly(A) RNA binding | SF3A2; GPATCH4; MRPL27; RBMX; EWSR1; RPL37A; MRPS31; TES; FLNA; CRKL |
| protein binding | ZNF193; CYB561; GCNT1; IL15; TBC1D14; ARPIN; PDK3; HIPK2; LILRA4; TIMP1 |
| protein domain specific binding | RUNX2; NR0B1; ZFP521; ARFIP2B; MRPL17; CASKIN1; WHRN; HIST1H4D; PICK1; CA |
ddx6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx6.
DCP1A; EDC3; YBX1; TRIM37
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