ddx6 Protein, DEAD (Asp-Glu-Ala-Asp) box helicase 6

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ddx6

Official Full Name	DEAD (Asp-Glu-Ala-Asp) box helicase 6
Background	The lymphoma-associated Rck/p54 gene product is a member of the DEAD box protein/RNA helicase family which has a variety of functions including translation initiation, pre-mRNA splicing, and ribosome assembly. Overexpression of human Rck in a guinea pig c
Synonyms	DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein

Species :
Chicken
Human
Mouse

Source :
HEK293
Mammalian Cell
Wheat Germ

Tag :
GST
His
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	DDX6-28328TH	Recombinant Human DDX6 protein, GST-tagged	Wheat Germ	GST
Human	DDX6-45H	Recombinant Human DDX6 protein, MYC/DDK-tagged	HEK293	Myc/DDK
Human	DDX6-6998HCL	Recombinant Human DDX6 293 Cell Lysate	HEK293	N/A
Mouse	DDX6-4433M	Recombinant Mouse DDX6 Protein	Mammalian Cell	His
Chicken	DDX6-1464C	Recombinant Chicken DDX6	Mammalian Cell	His
Chicken	DDX6-5430C	Recombinant Chicken DDX6	Mammalian Cell	His

Involved Pathway Protein Function Interacting Protein ddx6 Related Articles

ddx6 involved in several pathways and played different roles in them. We selected most pathways ddx6 participated on our site, such as Deadenylation-dependent mRNA decay, Gene Expression, RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Deadenylation-dependent mRNA decay	EIF4G1; EIF4A2; LSM6; EXOSC8; NT5C3B; D1BWG0212E; EIF4A1; EIF4B; DCP1B; C2orf29
Gene Expression	NSUN2; NRBF2B; BAZ2A; TBX5; ZNF563; NR1D2B; ZNF584; PHF1; ZNF75A; CLNS1A
RNA degradation	CNOT3B; PABPC1B; CNOT2; PFKM; EXOSC2; BTG2; WDR61; C1D; DCP2; PFKMB
mRNA decay by 5 to 3 exoribonuclease	DCP1B; LSM6; DDX6

ddx6 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx6 itself. We selected most functions ddx6 had, and list some proteins which have the same functions with ddx6. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PRKCB; ATP6V1A; DDX39A; DDX49; DDX3Y; GK; SMC5; VRK1; DYRK4; TSSK4
ATP-dependent RNA helicase activity	DDX10; DDX28; DDX21; DDX47; FAM120B; DDX31; SUPV3L1; ACTG2; EIF4A2; DDX25
RNA helicase activity	UAP1L1; FAM120B; DDX17; SKIV2L2; DHX16; CHST13; DHX15; RAD54B; DDX24; DDX6
helicase activity	DHX34; SHPRH; MCM6L; HLTF; SUPV3L1; DDX58; HELZ2; UPF1; ERCC6L; SMARCAL1
poly(A) RNA binding	Api5; VCP; TBL3; CNBP; HIST1H1E; MKI67IP; PES1; GNL3L; PPIB; ZFP326
protein binding	EPN3; NKX3-1; SMYD1; WDHD1; NDRG1; SH2D2A; SHISA5; CEP55; GBAS; FAIM
protein domain specific binding	MTOR; ARHGEF4; PHRF1; YWHAE1; TFDP2; SP100; NFASC; AKAP5; FAF1; EZR

ddx6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx6.

DCP1A; EDC3; YBX1; TRIM37

Johanneson, B; Chen, D; et al. Systematic validation of hypothesis-driven candidate genes for cervical cancer in a genome-wide association study. CARCINOGENESIS 35:2084-2088(2014).

Kawahara, C; Yokota, S; et al. DDX6 localizes to nuage structures and the annulus of mammalian spermatogenic cells. HISTOCHEMISTRY AND CELL BIOLOGY 141:111-121(2014).

ddx6 Protein, DEAD (Asp-Glu-Ala-Asp) box helicase 6

ddx6

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ddx6

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