ddx1

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ddx1

Official Full Name DEAD (Asp-Glu-Ala-Asp) box helicase 1
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin. [provided by RefSeq, Jul 2008]
Synonyms DDX1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DBP-RB; UKVH5d; ATP-dependent RNA helicase DDX1; DEAD box-1; DEAD box protein 1; DEAD box polypeptide 1; DEAD box protein retinoblastoma; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDX1-11888H Recombinant Human DDX1, His-tagged E.coli His
    Human DDX1-2461H Recombinant Human DDX1 Protein, GST-tagged Wheat Germ GST
    Human DDX1-26545TH Recombinant Human DDX1 Wheat Germ N/A
    Human DDX1-3083H Recombinant Human DDX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DDX1-4893H Recombinant Human DDX1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human DDX1-7021HCL Recombinant Human DDX1 293 Cell Lysate HEK293 N/A
    Mouse Ddx1-266M Recombinant Mouse Ddx1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse DDX1-4397M Recombinant Mouse DDX1 Protein Mammalian Cell His
    Rat DDX1-1816R Recombinant Rat DDX1 Protein Mammalian Cell His
    Cynomolgus Monkey DDX1-454C Recombinant Cynomolgus DDX1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque DDX1-1212R Recombinant Rhesus monkey DDX1 Protein, His-tagged Mammalian Cell His
    Chicken DDX1-6132C Recombinant Chicken DDX1 Mammalian Cell His
    Zebrafish DDX1-7828Z Recombinant Zebrafish DDX1 Mammalian Cell His

    ddx1 involved in several pathways and played different roles in them. We selected most pathways ddx1 participated on our site, such as Aldosterone synthesis and secretion, Neuronal System, Potassium Channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aldosterone synthesis and secretion ITPR2; ITPR1; ITPR3; Adcy4; CAMK2A; ATF4; PRKD3; ORAI1; PRKCB; HSD3B1
    Neuronal System KCNK6; KCNQ2A; GRIP1; KCNK2B; KCNJ1A.4; KCNMB2; KCNC1; BZRAP1; KCNA2; KCNA6A
    Potassium Channels KCNAB2; KCNK6; KCNK13B; KCNK3A; KCND1; KCNK16; DDX1; KCNK1A; KCNAB3; KCNF1A
    TWIK-releated acid-sensitive K+ channel (TASK) DDX1; KCNK3A
    Tandem pore domain potassium channels KCNK6; KCNK1; KCNK7; KCNK10B; KCNK3A; DDX1; KCNK2; KCNK1B; KCNK18; KCNK2B

    ddx1 has several biochemical functions, for example, S100 protein binding, ion channel activity, open rectifier potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx1 itself. We selected most functions ddx1 had, and list some proteins which have the same functions with ddx1. You can find most of the proteins on our site.

    Function Related Protein
    S100 protein binding S100A11; ANXA2; KCNK3; ATP2A2; S100A6; DDX1; AGER; S100B; AHNAK; FGF1A
    ion channel activity KCNS3A; TRPC7A; P2RX5; GRIA2A; TRPM1B; DDX1; TRPC7B; GJD3; KCNH5A; TRPM1
    open rectifier potassium channel activity KCNK3A; DDX1; KCNK3
    potassium channel activity KCNK13B; KCNC3A; KCNH5; KCNA6A; KCNG4A; KCNK1; KCNQ2; KCNK4; KCNA2B; KCNK3A
    potassium ion leak channel activity KCNK1A; KCNK9; KCNK7; KCNK5A; KCNK13B; KCNK2B; KCNK2; DDX1; KCNK1B; KCNK10B
    protein C-terminus binding DBNL; OPRL1; MRE11A; PQBP1; MIF4GD; MKI67; JAK2; SLC4A1; ECM1; TBL1X
    protein heterodimerization activity SDCBP2; HIST1H2AF; BMP7A; OSTB; IRAK3; PDSS2; HIST1H4J; IKZF4; BTBD11; CLCF1
    protein homodimerization activity TCF4; PVRL1A; PRDM6; PVRL1; DMRTC1B; RQCD1; KCNK3; CUBN; GSTM4; MITD1

    ddx1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx1.

    YWHAZ; RELB; SMAD2; NDRG1; NME7; 8-aha-camp; 8-aha-omethyladenosine; ssrna_ug

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