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DDX43

Official Full Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
Overview

The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression.
Synonyms

DDX43; DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; probable ATP-dependent RNA helicase DDX43; cancer/testis antigen 13; CT13; DKFZp434H2114; HAGE; DDX43_HUMAN; DEAD box protein 43; DEAD box protein HAGE; Helical antigen; Probable ATP dependent RNA helicase DDX43; OTTHUMP00000016742; DEAD-box protein 43;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Zebrafish

Source

E. coli
E.coli
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	DDX43-2491H	Recombinant Human DDX43 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	DDX43-457HCL	Recombinant Human DDX43 cell lysate		N/A		Inquiry
Human	DDX43-2605HF	Recombinant Full Length Human DDX43 Protein, GST-tagged	In Vitro Cell Free System	GST	648 amino acids	Inquiry
Human	DDX43-645H	Recombinant Human DDX43 protein, His-tagged	E. coli	His	264-648 aa	Inquiry
Mouse	Ddx43-6727M	Recombinant Mouse Ddx43 Protein (Mer1-Ser288), N-His tagged	E.coli	N-His	Mer1-Ser288	Inquiry
Mouse	Ddx43-6726M	Recombinant Mouse Ddx43 Protein (Met1-Ser268), N-His tagged	E.coli	N-His	Met1-Ser268	Inquiry
Zebrafish	DDX43-6452Z	Recombinant Zebrafish DDX43	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
DDX43 Related Articles

DDX43 involved in several pathways and played different roles in them. We selected most pathways DDX43 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

DDX43 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX43 itself. We selected most functions DDX43 had, and list some proteins which have the same functions with DDX43. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MERTK;WARS;MAGI1;ATP8B5;KIF11;CSF1RA;CKMT1B;SPO11;PEO1
ATP-dependent RNA helicase activity	DDX4;DDX56;DDX47;DDX41;DDX39AA;DDX10;DDX49;DDX28;DDX39A
RNA binding	HNRNPK;RPL34;NANOS3;RBM24A;FAM103A1;PRPF6;IREB2;SRBD1;RPL30

DDX43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX43 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX43.

Ambrosini, G; Khanin, R; et al. Overexpression of DDX43 Mediates MEK Inhibitor Resistance through RAS Upregulation in Uveal Melanoma Cells. MOLECULAR CANCER THERAPEUTICS 13:2073-2080(2014).

Abdel-Fatah, TMA; McArdle, SEB; et al. HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer. BRITISH JOURNAL OF CANCER 110:2450-2461(2014).