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Official Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
Background This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
Synonyms DDX46; DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; probable ATP-dependent RNA helicase DDX46; FLJ25329; KIAA0801; Prp5; PRPF5; PRP5 homolog; RNA helicase; DEAD box protein 46; Prp5-like DEAD-box protein; MGC9936
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDX46-11906H Recombinant Human DDX46, GST-tagged E.coli GST
    Mouse DDX46-4421M Recombinant Mouse DDX46 Protein Mammalian Cell His
    Rat DDX46-1822R Recombinant Rat DDX46 Protein Mammalian Cell His
    Rhesus Macaque DDX46-1220R Recombinant Rhesus monkey DDX46 Protein, His-tagged Mammalian Cell His
    Zebrafish DDX46-3063Z Recombinant Zebrafish DDX46 Mammalian Cell His

    ddx46 involved in several pathways and played different roles in them. We selected most pathways ddx46 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddx46 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome PRPF3; PRPF6; DHX8; DDX5; HSC70; SRSF7B; DHX38; PQBP1; SYF2; HNRNPK

    ddx46 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ddx46 itself. We selected most functions ddx46 had, and list some proteins which have the same functions with ddx46. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding HSP90AA1; RFC4; PKN3; CDK14; CNTN1B; ADCY1; MCM7; CAMKV; MYH11; HIPK1
    ATP-dependent RNA helicase activity DDX59; TDRD12; DHX34; DDX43; DHX9; DDX6; DHX35; DHX57; TDRD9; DHX38
    poly(A) RNA binding RPL28; RPS20; AHNAK; FNDC3A; FAM120A; DDX24; MRPL2; TBL3; MRPS23; ESF1

    ddx46 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddx46 here. Most of them are supplied by our site. Hope this information will be useful for your research of ddx46.

    SRPK2; NFKB1; RAC3; SF3A2; Sf3a1; recC; rpoB; ssrna_ag; SNW1

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