Active Recombinant Mouse Tnfsf11, Fc-tagged
Cat.No. : | Tnfsf11-247M |
Product Overview : | Mouse RANKL (aa 157-316) is fused at the N-terminus to the Fc portion of human IgG1. |
- Specification
- Gene Information
- Related Products
Description : | RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of Breast cancer. |
Source : | HEK293 Cells |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized. Contains PBS. |
Bio-activity : | Induces osteoclastogenesis of bone marrow-derived macrophages. |
Molecular Mass : | ~55kDa (SDS-PAGE) |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 0.1mg/ml after reconstitution. |
Gene Name : | Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Mus musculus ] |
Official Symbol : | Tnfsf11 |
Synonyms : | TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; OPG ligand; osteoprotegerin ligand; osteoclast differentiation factor; receptor activator of NF-kappaB ligand; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor-related activation-induced cytokine; ODF; OPG; OPGL; RANKL; Ly109l; Trance; |
Gene ID : | 21943 |
mRNA Refseq : | NM_011613 |
Protein Refseq : | NP_035743 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Osteoblast, organism-specific biosystem; Osteoclast, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; |
Function : | cytokine activity; protein binding; receptor activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor superfamily binding; |
Products Types
◆ Recombinant Protein | ||
TNFSF11-2025R | Recombinant Rat TNFSF11 Protein | +Inquiry |
Tnfsf11-85M | Active Recombinant Mouse Tnfsf11 Protein (Pro143-Asp316), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF11-3253H | Active Recombinant Human TNFSF11 protein(Gly 63-Asp 244), rFc-tagged | +Inquiry |
TNFSF11-255M | Active Recombinant Mouse TNFSF11 Protein | +Inquiry |
TNFSF11-2024M | Recombinant Mouse TNFSF11 Protein | +Inquiry |
◆ Lysates | ||
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
TNFSF11-001CCL | Recombinant Cynomolgus TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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