TNFSF15
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Official Full Name
tumor necrosis factor (ligand) superfamily, member 15
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Overview
TL1A, also known as TNF ligand-related molecule 1, vascular endothelial growth inhibitor, and TNF ligand superfamily member 15, is a type II membrane protein with a predicted molecular weight of 28 kD. TL1A can also be found as a secreted protein as a res -
Synonyms
TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; MGC129934; MGC129935; TL1; TL1A; TNF ligand related molecule 1; TNF superfamily ligand TL1A; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor 192A; VEGI; VEGI192A; TNF ligand-related molecule 1; vascular endothelial growth inhibitor-192A;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Ala61-Leu252
- Chicken
- Cynomolgus/Rhesus macaque
- Homo sapiens (Human)
- Human
- Mouse
- Rat
- Rhesus Macaque
- Rhesus monkey
- E.coli
- E.coli expression system
- HEK293
- Human Cell
- Human Cells
- Mammalian Cell
- N-His-Avi
- Biotin
- Fc
- Flag
- hIgG4
- His
- Avi
- T7
- mFc
- N
- Non
- rFc
- The N
- terminal His
- AviTag™
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
- TNFSF15 Related Signal Pathway
TNFSF15 involved in several pathways and played different roles in them. We selected most pathways TNFSF15 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFSF15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TNFRSF21;Il23a; Il12b;IL2RG;TNFRSF11A;IL2RB;IL22;CXCL2;TNF;IFNK |
TNFSF15 has several biochemical functions, for example, cytokine activity, death receptor binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFSF15 itself. We selected most functions TNFSF15 had, and list some proteins which have the same functions with TNFSF15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | GDF7;FAM3B;NDR1;IFNA14;IL36G;IL31;INHBAA;C1QTNF4;BMP2 |
| death receptor binding | FADD;BID;RIPK1;FEM1B;NOL3;MYD88;PRDM4;PIDD1;TMBIM1 |
| receptor binding | FGF20A;APLN;AMACR;F2RL1;POMC;ICOSLG;GNPAT;GUSB;FASLG |
| tumor necrosis factor receptor binding | TNFSF10L;TRAP1;TRADD;TRAF3;TNFSF12;TRAF1;TNFSF13;FASLG;TNFSF10 |
TNFSF15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFSF15 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFSF15.
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Customer Reviews (3)
Write a reviewThey keep up with the latest research findings and continually refine their product based on customer feedback and emerging scientific trends.
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Q&As (5)
Ask a questionTNFSF15 interacts with receptors on immune cells, influencing their activity and contributing to the overall regulation of immune responses.
Several clinical trials are underway to evaluate the efficacy and safety of therapies targeting TNFSF15 in autoimmune diseases.
TNFSF15 levels may serve as a biomarker for certain autoimmune conditions, aiding in the diagnosis and monitoring of disease progression.
TNFSF15 is considered a promising target for drug development, and ongoing research aims to identify compounds that modulate its activity effectively.
In IBD, TNFSF15 is believed to be involved in the inflammation process, contributing to the chronic nature of the disease.
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