"PLA2G12A" Related Products

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Recombinant Human PLA2G12A, His-tagged

Cat.No.: PLA2G12A-30734TH
Product Overview: Recombinant mature full length protein, corresponding to amino acids 23-189 of the Human Phospholipase A2 XII precursor , with a 16 amino acid N-terminal His tag. 183 total amino acids.
Description: Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al.
Conjugation: HIS
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 0.01M Tris buffer, pH 8.6
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MRGSHHHHHH GMASHMQEQA QTTDWRATLK TIRNGVHKIDTYLNAALDLL GGEDGLCQYK CSDGSKPFPR YGYKPSPPNGCGSPLFGVHL NIGIPSLTKC CNQHDRCYET CGKSKNDCDEEFQYCLSKIC RDVQKTLGLT QHVQACETTV ELLFDSVIHLGCKPYLDSQR AACRCHYEEK TDL
Gene Name: PLA2G12A phospholipase A2, group XIIA [ Homo sapiens ]
Official Symbol: PLA2G12A
Synonyms: PLA2G12A; phospholipase A2, group XIIA; phospholipase A2, group XII , PLA2G12; group XIIA secretory phospholipase A2;
Gene ID: 81579
mRNA Refseq: NM_030821
Protein Refseq: NP_110448
MIM: 611652
Uniprot ID: Q9BZM1
Chromosome Location: 4q25
Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem;
Function: calcium ion binding; calcium-dependent phospholipase A2 activity; hydrolase activity;

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