PLA2G10

  • Official Full Name

    phospholipase A2, group X
  • Overview

    Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipi
  • Synonyms

    PLA2G10;phospholipase A2, group X;group 10 secretory phospholipase A2;GXPLA2;Group X secretory phospholipase A2;GXSPLA2;Phosphatidylcholine 2 acylhydrolase GX;Phospholipase A2 group X;SPLA2;sPLA2X;sPLA2-X;GX sPLA2;OTTHUMP00000045725;phosphatidylcholine 2-acylhydrolase 10

Recombinant Proteins

  • Rat
  • Chicken
  • Human
  • Mouse
  • Mammalian Cells
  • HEK293
  • E.coli
  • Insect Cells
  • His
  • Fc
  • Non
  • Flag
  • Myc
  • Avi
  • GST
  • DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
PLA2G10-4484R Recombinant Rat PLA2G10 Protein Mammalian Cells Rat His
PLA2G10-4485R Recombinant Rat PLA2G10 Protein, Fc tagged HEK293 Rat Fc
PLA2G10-4098C Recombinant Chicken PLA2G10 Mammalian Cells Chicken His
PLA2G10-70H Recombinant Human phospholipase A2, group X, His-tagged E.coli Human His
PLA2G10-3145HCL Recombinant Human PLA2G10 293 Cell Lysate HEK293 Human Non
PLA2G10-103HFL Recombinant Full Length Human PLA2G10 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
Pla2g10-1151M Recombinant Mouse Pla2g10 protein, His&Myc-tagged E.coli Mouse His&Myc 29-151aa
Pla2g10-1272M Recombinant Mouse Pla2g10 protein, His&Myc-tagged Insect Cells Mouse His&Myc 29-151aa
PLA2G10-1691H Recombinant Human PLA2G10 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
PLA2G10-1691H-B Recombinant Human PLA2G10 Protein Pre-coupled Magnetic Beads HEK293 Human
Pla2g10-1944M Recombinant Mouse Pla2g10 Protein, His-tagged E.coli Mouse His Gly29-Asn151
PLA2G10-307H Recombinant Human PLA2G10 protein, His-GST&Myc-tagged E.coli Human GST&His&Myc 43-165aa
PLA2G10-4144R Recombinant Rat PLA2G10 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
PLA2G10-4144R-B Recombinant Rat PLA2G10 Protein Pre-coupled Magnetic Beads HEK293 Rat
Pla2g10-4894M Recombinant Mouse Pla2g10 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
PLA2G10-5207H Recombinant Human PLA2G10 Protein (Glu32-Asp165), N-His tagged E.coli Human His Glu32-Asp165
Pla2g10-7844R Recombinant Rat Pla2g10 protein, His&Myc-tagged E.coli Rat His&Myc 29-151a.a.

    Involved Pathway

    PLA2G10 involved in several pathways and played different roles in them. We selected most pathways PLA2G10 participated on our site, such as Glycerophospholipid metabolism,Ether lipid metabolism,Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fat digestion and absorption AGPAT1,DGAT1,PNLIPRP2,PLA2G2E,MOGAT2,PPAP2B,PLA2G2A,PPAP2A,CD36,CLPS
    Glycerophospholipid metabolism PPAP2C,PLA2G3,LCAT,LPIN1,DGKQ,GPD1,PLA2G4C,AGPAT9L,CDIPT,PPAP2D
    Ether lipid metabolism PPAP2B,PLA2G2F,CEPT1B,PLD3,PLA2G3,PLA2G6,PLA2G4C,UGT8A,EPT1,TMEM86B
    Pancreatic secretion PNLIPRP1,RAB27B,TRPC1,ATP1B2,ATP2A2,PLA2G2A,Cel,ATP2B1,CLCA4,CPA3
    Vascular smooth muscle contraction PPP1R14AB,CACNA1C,ARHGEF12,PTGIR,PRKCH,PRKACB,PRKCBB,ADRA1BB,ADCY1B,PLCB4
    Arachidonic acid metabolism DPEP1,FAAH2A,CYP4T8,DPEP2,CYP2P7,CBR3,PTGDS,CYP2B19,CYP2U1,TBXAS1
    Ras signaling pathway PIK3R2,FGF6,RAP1B,NRAS,PIK3CB,FGF2,FGF19,HGF,Fasl,PLA2G1B
    Linoleic acid metabolism CYP2C9,CYP2J6,CYP2C19,PLA2G4D,PLA2G2A,PLA2G2F,CYP2J5,PLB1,DHRS13L1,PLA2G6
    alpha-Linolenic acid metabolism ACOX3,PLA2G4C,PLA2G2F,FADS2,PLA2G12A,ACAA1A,PLA2G5,PLA2G2A,ACAA1,PLA2G2E

    Protein Function

    PLA2G10 has several biochemical functions, for example, calcium ion binding,phospholipase A2 activity,phospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G10 itself. We selected most functions PLA2G10 had, and list some proteins which have the same functions with PLA2G10. You can find most of the proteins on our site.

    Function Related Protein
    phospholipase activity CELL,CES1C,LIPC,LIPM,ABHD6,LIPH,LIPK,DAGLB,LIPG,PNPLA7
    calcium ion binding PRKCSH,S100A5,DLC,FAT3A,RCVRNA,SERPINB1A,PCDH2AB1,S100A3,S100A4,CRB2B
    phospholipase A2 activity PLA2G2E,PLA2G16,PNPLA3,PLA2G2A,PLA2G12B,PLA2G4AA,LCAT,ABHD3,PLA2G1B,PLA2G2D

    Interacting Protein

    PLA2G10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G10.

    MYO10

    Resources

    References

    • Sin, BA; Akdis, M; et al. T-cell and antibody responses to phospholipase A(2) from different species show distinct cross-reactivity patterns. ALLERGY 66:1513-1521(2011).
    • Shaposhnik, Z; Wang, X; et al. The synergistic inhibition of atherogenesis in apoE(-/-) mice between pravastatin and the sPLA(2) inhibitor varespladib (A-002). JOURNAL OF LIPID RESEARCH 50:623-629(2009).

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