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PLA2G4C

  • Official Full Name

    phospholipase A2, group IVC (cytosolic, calcium-independent)

  • Overview

    Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
  • Synonyms

    PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLA2G4C-1753H Recombinant Human PLA2G4C, His-tagged E.coli His 190-541aa
Human PLA2G4C-3140HCL Recombinant Human PLA2G4C 293 Cell Lysate HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerophospholipid metabolismPLA2G4F;DGKG;DGKB;PTDSS1A;EPT1;PLA2G10;PLA2G4C;PCYT1BB;CHKB
Ether lipid metabolismPPAP2A;PLA2G12B;LPCAT4;PLA2G4A;CEPT1B;PAFAH1B1A;ENPP6;CEPT1;PPAP2CB
Arachidonic acid metabolismGPX1;CYP2C8;PLA2G4C;CYP2J5;GPX2;ALOX5AP;CYP4F22;GPX3;PLA2G10
Linoleic acid metabolismCYP2P6;CYP3A25;CYP2C8;CYP3A41B;CYP2P10;PLA2G2A;PLA2G3;PLA2G12B;DHRS13L1
alpha-Linolenic acid metabolismPLA2G3;PLA2G12B;PLA2G4F;PLA2G4A;ACAA1A;PLA2G4C;PLA2G6;ACOX1;PLA2G4D
Metabolic pathwaysPRODH2;ACAA1;TPK1;GCNT4;ACSS1;AKR1B10;GNPDA1;CDIPT;EXT1A
MAPK signaling pathwayRASA2;HSPA6;MAP3K6;PDGFB;ELK4;Pdgfa&Pdgfb;PDGFAA;HSPA1B;FGF10A
Ras signaling pathwayPIK3CA;RGL2;RAP1A;PAK3;VEGFA;IGF1;FGF16;REL;SHC2
Phospholipase D signaling pathwaySHC4;INSR;Kitl;GRB2;CYTH2;HRAS;SPHK1;GRM6;PLA2G4D
Vascular smooth muscle contractionPPP1R12B;CALML5;GNA12;ADCY2B;PRKCE;ROCK1;MYL6;MAPK3;ITPR3
VEGF signaling pathwayMAPK14A;MAPK13;PRKCA;PRKCG;PTK2;PIK3R3A;PTK2AA;NFATC2;AKT1
Platelet activationVASP;PPP1CB;GP1BB;FCER1G;SNAP23;PRKACA;PLA2G4D;GNAS;GP5
Fc epsilon RI signaling pathwayPLA2G4C;MAPK1;SOS1;MAPK9;GRB2;VAV1;MAPK3;GAB2;PLA2G4D
Glutamatergic synapseGRIN2A;GNG5;GRIK2;GRIA1;GRIN2D;GNB3;GRM4;GRIK4;GRIN2B
Serotonergic synapseALOX8;GNB3;TPH2;GNB1;HTR6;GNAI2;PTGS1;MAP2K1;HTR7
Long-term depressionGRIA2;PRKCG;PLCB2;PRKG2;ITPR3;KRAS;NOS1;GRIA1;HRAS
Inflammatory mediator regulation of TRP channelsPLA2G4D;CYP2J2;GNAQ;MAP2K3;CYP2J5;SRC;CYP2J6;PPP1CC;NGF
GnRH signaling pathwayKRAS;GNRHR1;MAPK8A;PLCB4;CAMK2D1;PLA2G4AA;CACNA1DA;MAP2K4B;MAP2K6
Ovarian steroidogenesisSTAR;HSD3B6;ALOX5;IGF1R;GDF9;LHB;CYP2J5;PRKACB;HSD3B5
Oxytocin signaling pathwayPLA2G4D;MAP2K2;CACNG4;CALML5;ROCK1;CAMK2G;CALM4;CAMK4;RYR1
Choline metabolism in cancerPCYT1A;HIF1A;PLA2G4B;PIP5K1A;PDPK1;TSC1;PLCG1;PPAP2C;MAP2K2

PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.

Function Related Protein
calcium-independent phospholipase A2 activityPLA2G15;PLA2G4C;PLA2G7;PNPLA8
phospholipid bindingAPOA1;AGAP1;VAMP2;PICALMA;SYTL4;GRK5;LC3;NSMAF;APOM

PLA2G4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4C here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4C.

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