PLA2G4D
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Official Full Name
phospholipase A2, group IVD (cytosolic) -
Overview
The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2;position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 (PubMed 14709560)). -
Synonyms
PLA2G4D;phospholipase A2, group IVD (cytosolic);cytosolic phospholipase A2 delta;cPLA2delta;cPLA2 delta;Phospholipase A2 group IVD;cPLA2-delta;phospholipase A2 delta, cytosolic
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
PLA2G4D involved in several pathways and played different roles in them. We selected most pathways PLA2G4D participated on our site, such as Glycerophospholipid metabolism,Ether lipid metabolism,Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fc epsilon RI signaling pathway | NRAS,MAPK1,PIK3R2,PIK3R3,LYN,INPP5D,PRKCA,MAPK9,PLA2G4F,SYK |
| Vascular smooth muscle contraction | ADCY1A,CACNA1C,MAP2K2,PLA2G4F,PPP1R14AB,CALM,ITPR3,PLA2G3,MYH11,GNA11A |
| Metabolic pathways | GALNT1,EPRS,ST6GAL2A,BDH1,FECH,AK9,PCK1,DAO.3,CYP3A65,NDUFS2 |
| Linoleic acid metabolism | CYP2P7,PLA2G4C,CYP2C8,PLA2G12B,PLA2G2A,PLA2G4A,CYP2C37,DHRS13L1,CYP2C38,CYP3A41B |
| MAPK signaling pathway | MAPK8B,CACNB3,RRAS2,CASP3B,PLA2G4AA,MAP2K6,FGFR4,TNF,FOS,TRAF2 |
| Ether lipid metabolism | PLA2G2E,PLD3,PLA2G12B,PLA2G12A,PLA2G2F,LPCAT4,PLA2G5,PLA2G7,CHPT1,GAL3ST1 |
| Phospholipase D signaling pathway | INS,PIP5K1C,AVPR1A,RHOA,GRM5,KITLG,PLCG1,PLCB4,GNA12,MAPK3 |
| Choline metabolism in cancer | FOS,PCYT1A,HIF1A,HRAS,Pdgfa&Pdgfb,CHKA,NRAS,PDGFRA,RAF1,WASL |
| alpha-Linolenic acid metabolism | ACOX3,ACAA1A,PLA2G2F,PLA2G2A,PLA2G4C,PLA2G4F,PLA2G2D,PLA2G3,PLA2G12A,PLA2G2E |
Protein Function
PLA2G4D has several biochemical functions, for example, metal ion binding,phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4D itself. We selected most functions PLA2G4D had, and list some proteins which have the same functions with PLA2G4D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ARFGAP3,GTSF1,ZNF839,DBR1,ZFP14,ZFP260,MYCBP2,AGO2,ALOX8,NUDT17 |
| phospholipase A2 activity | PNPLA3,PRDX6,PLA2G4A,PLA2G4AA,OC90,RARRES3,PLA2G12B,LCAT,PLA2G6,PLA2G2E |
Interacting Protein
PLA2G4D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4D here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4D.
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