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Official Full Name phospholipase A2, group IID
Background Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. PLA is subdivided into PLA1 which cleave phospholipids at the sn-1 ester bond and PLA2, which cleave at the sn-2 bond. Their most common substrate is phosphatidylcholine, which generates lysophosphatidylcholine and arachidonic acid. PLA is regulated by phosphorylation and by intracellular Ca2+ concentrations. Phospholipases are ubiquitously expressed and have diverse biological functions including roles in inflammation, cell growth, signaling and death and maintenance of membrane phospholipids.
Synonyms PLA2G2D; phospholipase A2, group IID; group IID secretory phospholipase A2; sPLA2S; PLA2IID; sPLA2-IID; GIID sPLA2; secretory phospholipase A2s; phosphatidylcholine 2-acylhydrolase 2D; secretory-type PLA, stroma-associated homolog; SPLASH
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Tag :
    • Fc
    • His
    • T7
    • HlgG1 Fc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse PLA2G2D-902M Recombinant Mouse PLA2G2D Protein (Met1-Cys144), HlgG1 Fc-tagged HEK293 HlgG1 Fc
    Human PLA2G2D-29526TH Recombinant Human PLA2G2D, His-tagged E.coli His
    Human PLA2G2D-365H Recombinant Human PLA2G2D, Fc-tagged Human Cell Fc
    Human PLA2G2D-463H Recombinant Human PLA2G2D Protein, Fc-tagged HEK293 Fc
    Human PLA2G2D-68H Recombinant Human phospholipase A2, group IID, His-tagged E.coli His
    Human PLA2G2D-757HCL Recombinant Human PLA2G2D cell lysate Human Cell N/A
    Human PLA2G2D-8493H Recombinant Human PLA2G2D Protein E.coli N/A
    Mouse Pla2g2d-489M Recombinant Mouse Pla2g2d protein, His-tagged E.coli His
    Rat Pla2g2d-1477R Recombinant Rat Pla2g2d protein, His & T7-tagged E.coli His/T7

    pla2g2d involved in several pathways and played different roles in them. We selected most pathways pla2g2d participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with pla2g2d were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism CDS2; PCYT1AA; CHAT; AGPAT9; PPAP2B; PTDSS2; PCYT2; PEMT; GPD1L; GPD1A
    Ether lipid metabolism PLA2G3; PLA2G2D; PLA2G4B; PPAP2D; LPCAT1; AGPS; CEPT1; UGT8A; LPCAT2; GAL3ST1A
    Arachidonic acid metabolism CYP4B1; PTGES; CYP2C38; ALOX15; CYP2AD2; ALOX5; CYP2P8; PTGS2B; LTC4S; ALOX12B
    Linoleic acid metabolism CYP2C37; PLA2G10; CYP3A25; CYP2C55; PLA2G2A; PLA2G6; CYP2C39; CYP2C54; CYP3A41A; CYP2C9
    alpha-Linolenic acid metabolism ACAA1; ACAA1A; PLA2G2D; PLA2G4D; PLA2G4A; PLA2G5; PLA2G10; ACOX1; PLA2G4F; ACOX3
    Metabolic pathways ATP6V0B; ADH7; ALG13; GAA; BTD; HADHB; GALNTL2; GALNT14; UCK2A; UROD
    Ras signaling pathway FGF3; PDGFRA; HRAS; INS; PDGFC; ELK1; CALM1; KIT; GAB1; PGF
    Vascular smooth muscle contraction CALM1A; PLA2G12A; PPP1R12B; CALML5; ARHGEF11; PLA2G4D; PPP1R12C; RHOAA; RAF1B; GNA15.1
    Pancreatic secretion ATP1A4; PNLIP; Slc4a2; CLCA2; RAP1B; SLC9A1; RAC1; CELA2B; LOC780933; PRKCG
    Fat digestion and absorption ACAT2; APOA1; PPAP2C; FABP2; APOB; CD36; PLA2G2E; PLA2G2A; PLA2G10; LIPF

    pla2g2d has several biochemical functions, for example, calcium ion binding, heparan sulfate proteoglycan binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pla2g2d itself. We selected most functions pla2g2d had, and list some proteins which have the same functions with pla2g2d. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding RAB11FIP4; STIM2; SLC25A23; PCDH21; EHD1B; SYTL3; ATP2A2; S100S; LRP2A; PCDHB6
    heparan sulfate proteoglycan binding PLA2G2D; AGRN; HRG; AZU1; SEMA5A; SLIT2; Itgam&Itgb2; HPSE2; COMP; FST
    heparin binding CFH; NRP1; SELL; ADAMTS1; CCDC80; AAMP; SMOC2; EPYC; OGN; FGFR1A
    phospholipase A2 activity PNPLA3; PLA2G4AA; PLA2G12B; PLA2G2D; RARRES3; LCAT; PLA2G1B; PLA2G2A; PRDX6; PLA2G4D

    pla2g2d has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pla2g2d here. Most of them are supplied by our site. Hope this information will be useful for your research of pla2g2d.

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