pla2g1b
Share
  • Official Full Name
  • phospholipase A2, group IB (pancreas)
  • Background
  • Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known;varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2;enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to;venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine,;macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986;(PubMed 3028739)) .
  • Synonyms
  • PLA2G1B; phospholipase A2, group IB (pancreas); PLA2, PLA2A, PPLA2; phospholipase A2; group IB phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; PLA2; PLA2A; PPLA2; MGC119834; MGC119835
Cat.#:PLA2G1B-1878HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PLA2G1B Protein, MYC/DDK-tagged
+Inquiry
Cat.#:PLA2G1B-171HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PLA2G1B, His-tagged
+Inquiry
Cat.#:PLA2G1B-1751HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G1B, His-tagged
+Inquiry
Cat.#:PLA2G1B-254HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PLA2G1B Protein, His-tagged
+Inquiry
Cat.#:PLA2G1B-31023THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G1B, His-tagged
+Inquiry
Cat.#:PLA2G1B-625HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human PLA2G1B, His-tagged
+Inquiry
Cat.#:PLA2G1B-66HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Phospholipase A2, Group IB (Pancreas), His-tagged
+Inquiry
Cat.#:Pla2g1b-1185MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pla2g1b, His tagged
+Inquiry
Cat.#:PLA2G1B-4487RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PLA2G1B Protein
+Inquiry
Cat.#:PLA2G1B-3919CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PLA2G1B
+Inquiry
Cat.#:PLA2G1B-2200HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human PLA2G1B cell lysate
+Inquiry
Cat.#:PLA2G1B-2033MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PLA2G1B cell lysate
+Inquiry

Involved Pathway

PLA2G1B involved in several pathways and played different roles in them. We selected most pathways PLA2G1B participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid metabolism
CEPT1; PLA2G6; PPAP2A; PLA2G16; GPD1B; DGKG; DGKB; PLA2G2A; PLA2G3; PNPLA7
Ether lipid metabolism
PAFAH1B1B; PLA2G2A; PAFAH1B1A; ENPP6; CEPT1B; PLA2G4AA; PLA2G2F; UGT8A; PLA2G3; PLA2G12B
Arachidonic acid metabolism
PLA2G2D; CBR1; PLA2G4C; AKR1C3; ALOX5A; CYP2P7; CYP2C55; CYP2C45; PLA2G4F; ALOX5B.2
Linoleic acid metabolism
CYP2P9; CYP2C50; DHRS13L1; PLA2G12B; CYP3A25; CYP2P10; CYP2J2; CYP2C45; CYP2C70; PLA2G3
alpha-Linolenic acid metabolism
PLA2G4C; PLA2G6; PLA2G2E; PLA2G4AA; PLA2G1B; PLA2G2A; PLA2G2D; PLA2G2F; PLA2G12B; ACAA1A
Metabolic pathways
POLR2EB; TM7SF2; AHCYL2; NMNAT1; COX5AA; HADHAB; ctaG; PRIM1; ACADL; ACACB
Ras signaling pathway
GNB1; RALB; NGF; HTR7; INS; RHOA; RELA; PLA2G3; ETS1; GNGT2
Vascular smooth muscle contraction
CALCRLA; ACTA2; RHOAB; PLA2G2E; KCNMB2; PRKCBA; PRKCH; ITPR3; CACNA1SB; PPP1R14A
Pancreatic secretion
AMY2A4; SCTR; ATP1A2; PLA2G2E; PLCB4; PLA2G1B; RHOA; PNLIPRP2; ATP2A1; ATP1B4
Fat digestion and absorption
AGPAT1; PLA2G1B; PPAP2A; PLA2G2A; DGAT2; MOGAT3; PPAP2B; APOA1; PLA2G2F; PLA2G3

Protein Function

PLA2G1B has several biochemical functions, for example, bile acid binding, calcium ion binding, calcium-dependent phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G1B itself. We selected most functions PLA2G1B had, and list some proteins which have the same functions with PLA2G1B. You can find most of the proteins on our site.
Function
Related Protein
Function bile acid binding
Related Protein PLA2G1B; FABP1; STARD5; AKR1C21; FABP10A; NR1H4; FABP6; PYGL; AKR1C2
Function calcium ion binding
Related Protein LDLR; CDH10; ANXA5B; MYL3; NKD2; FSTL4; MCFD2; MAN1A1; MMP1A; PCDH2AB2
Function calcium-dependent phospholipase A2 activity
Related Protein PLA2G1B; PLA2G5; PLA2G12A; PLA2G3; PLA2G4B; PLA2G4A; PLA2G4F; PLA2G2A
Function phospholipase A2 activity
Related Protein PLA2G10; PLA2G2A; ABHD3; PLA2G2F; PLA2G16; RARRES3; OC90; PLA2G1B; PRDX6; PLA2G4A
Function receptor binding
Related Protein A2M; TNFSF4; PTK2AB; PDGFRB; WNT7A; HLA-G; AKAP9; FRK; RASA1; FGF11A

Interacting Protein

PLA2G1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G1B here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G1B.
SOCS2

PLA2G1B Related Articles

Karray, A; Ben Ali, Y; et al. Drastic changes in the tissue-specific expression of secreted phospholipases A2 in chicken pulmonary disease. BIOCHIMIE 94:451-460(2012).
Karray, A; Zarai, Z; et al. Kinetic properties of pancreatic and intestinal sPLA2 from chicken and mammals using the monomolecular film technique. JOURNAL OF COLLOID AND INTERFACE SCIENCE 363:620-625(2011).