Recombinant Human Regulator Of G-protein Signaling 16, His-tagged RGS16-2031H

Cat. No.:	RGS16-2031H
Product Overview:	Recombinant Human RGS16 protein with his tag was expressed inE.coliand purified by using conventional chromatography techniques, 24.9 kDa (222aa).
Description:	RGS16, also known as regulator of G-protein signaling 16, belongs to "regulator of G protein signaling" family and negatively regulates G protein coupled receptor signalling. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP bound form. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade.
Source:	E.coli.
Form:	Liquid. In Phosphate Buffered Saline (pH7.4) containing 20% glycerol 0.1M NaCl.
Purity:	> 90% by SDS – PAGE.
Concentration:	0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids:	MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS EL GCD TGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLLSSKNGVAAFH AFLKT EFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTRTLMEKDSYPR FLKSPAYRDL AAQASAASAT LS SCSLDEPS HT.
Storage:	can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

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Gene Name:	RGS16 regulator of G-protein signaling 16 [ Homo sapiens ]
Synonyms:	regulator of G-protein signaling 16; RGS-R; A28-RGS14; A28-RGS14P; RGS16; hRGS-r; retinal-specific RGS; retinally abundant regulator of G-protein signaling; RGSR; RGS-r; Retinally abundant regulator of G-protein signaling
Gene ID:	6004
mRNA Refseq:	NM_002928
Protein Refseq:	NP_002919
MIM:	602514
UniProt ID:	O15492
Chromosome Location:	1q25-q31
Function:	GTPase activator activity; calmodulin binding; signal transducer activity