Cat. No.:	IGF1-456H
Product Overview:	Recombinant Human Insulin-like Growth Factor 1 (Somatomedin C) is expressed inyeast.
Description:	Human IGF-I is a potent mitogen for mesenchymally-derived cells. It is composed of 70 amino acid residues, and is 62% homologous with human IGF-II.
Source:	Human IGF-I is produced by genetically engineeredyeast, and purified by sequential chromatography.
Molecular Weight:	7.5 kDa.
Biological Activity:	The material is active in a receptor-binding assay using a membrane preparation from placenta.
Purity:	Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
Storage And Reconstitution:	Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80 °C is recommended.

Gene Name:	IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
Synonyms:	IBP1; IGF-IA; IGF-IB; IGFI; MGF; Somatomedin-C; Insulin-like growth factor IA precursor; Insulin-like growth factor IB precursor; Mechano growth factor; insulin-like growth factor 1; IGF1; insulin-like growth factor 1 (somatomedin C)
Gene ID:	3479
mRNA Refseq:	NM_000618.3
Protein Refseq:	NP_000609.1
MIM:	147440
UniProt ID:	P01343; P05019
Chromosome Location:	12q22-q23
Pathway:	Focal adhesion, Glioma, Long-term depression, Melanoma, Prostate cancer, mTOR signaling pathway
Function:	Growth factor activity, Hormone activity, Insulin-like growth factor receptor binding, Prothoracicotrophic hormone activity

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