Cat. No. :	IGF1-456H
Product Overview :	Recombinant Human Insulin-like Growth Factor 1 (Somatomedin C) is expressed inyeast.
Description :	Human IGF-I is a potent mitogen for mesenchymally-derived cells. It is composed of 70 amino acid residues, and is 62% homologous with human IGF-II.
Source :	Human IGF-I is produced by genetically engineeredyeast, and purified by sequential chromatography.
Molecular Weight :	7.5 kDa.
Biological Activity :	The material is active in a receptor-binding assay using a membrane preparation from placenta.
Purity :	Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
Storage And Reconstitution :	Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80 °C is recommended.

Gene Name :	IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
Synonyms :	IBP1; IGF-IA; IGF-IB; IGFI; MGF; Somatomedin-C; Insulin-like growth factor IA precursor; Insulin-like growth factor IB precursor; Mechano growth factor; insulin-like growth factor 1; IGF1; insulin-like growth factor 1 (somatomedin C)
Gene ID :	3479
mRNA Refseq :	NM_000618.3
Protein Refseq :	NP_000609.1
MIM :	147440
UniProt ID :	P01343; P05019
Chromosome Location :	12q22-q23
Pathway :	Focal adhesion, Glioma, Long-term depression, Melanoma, Prostate cancer, mTOR signaling pathway
Function :	Growth factor activity, Hormone activity, Insulin-like growth factor receptor binding, Prothoracicotrophic hormone activity

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