Recombinant Human Insulin-like Growth Factor 1 (Somatomedin C)

• Cat.No.: IGF1-456H
• Product Overview: Recombinant Human Insulin-like Growth Factor 1 (Somatomedin C) is expressed inyeast.

Specification

• Cat. No.: IGF1-456H
• Description: Human IGF-I is a potent mitogen for mesenchymally-derived cells. It is composed of 70 amino acid residues, and is 62% homologous with human IGF-II.
• Source: Human IGF-I is produced by genetically engineeredyeast, and purified by sequential chromatography.
• Molecular Weight: 7.5 kDa.
• Biological Activity: The material is active in a receptor-binding assay using a membrane preparation from placenta.
• Purity: Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
• Storage And Reconstitution: Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80 °C is recommended.

Gene Information

• Gene Name: IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
• Synonyms: IBP1; IGF-IA; IGF-IB; IGFI; MGF; Somatomedin-C; Insulin-like growth factor IA precursor; Insulin-like growth factor IB precursor; Mechano growth factor; insulin-like growth factor 1; IGF1; insulin-like growth factor 1 (somatomedin C)
• Gene ID: 3479
• mRNA Refseq: NM_000618.3
• Protein Refseq: NP_000609.1
• MIM: 147440
• UniProt ID: P01343; P05019
• Chromosome Location: 12q22-q23
• Pathway: Focal adhesion, Glioma, Long-term depression, Melanoma, Prostate cancer, mTOR signaling pathway
• Function: Growth factor activity, Hormone activity, Insulin-like growth factor receptor binding, Prothoracicotrophic hormone activity