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Official Full Name insulin-like growth factor 2 mRNA binding protein 1
Background This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms IGF2BP1; insulin-like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA-binding protein 1; IGF II mRNA binding protein 1; IMP 1; ZBP-1; VICKZ family member 1; zipcode-binding protein 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-bind
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IGF2BP1-01H Recombinant Human IGF2BP1 Protein, His-tagged E. coli His
    Human IGF2BP1-106H Recombinant Human IGF2BP1, MYC/DDK-tagged HEK293 Myc/DDK
    Human IGF2BP1-4160H Recombinant Human IGF2BP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IGF2BP1-5265HCL Recombinant Human IGF2BP1 293 Cell Lysate HEK293 N/A
    Human IGF2BP1-526H Recombinant Human IGF2BP1 protein, GST-tagged Wheat Germ GST
    Mouse IGF2BP1-8066M Recombinant Mouse IGF2BP1 Protein Mammalian Cell His
    Mouse Igf2bp1-987M Recombinant Mouse Igf2bp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rhesus Macaque IGF2BP1-2217R Recombinant Rhesus monkey IGF2BP1 Protein, His-tagged Mammalian Cell His
    Chicken IGF2BP1-6628C Recombinant Chicken IGF2BP1 Mammalian Cell His
    Zebrafish IGF2BP1-4467Z Recombinant Zebrafish IGF2BP1 Mammalian Cell His

    igf2bp1 involved in several pathways and played different roles in them. We selected most pathways igf2bp1 participated on our site, such as BDNF signaling pathway, Gene Expression, Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with igf2bp1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    BDNF signaling pathway SIRPA; GNB2L1; CDKL5; FRS3; CNR1; JAK2; CSNK2A1P; DPYSL2; EIF4EBP1; EGR1
    Gene Expression ZNF334; ZNF613; SET; ZMAT5; U2AF2; HNRNPA0A; ZNF792; ZNF454; DNMT3B; ADAR
    Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA IGF2BP3; IGF2BP1; IGF2BP2
    MAPK family signaling cascades MAPK4; SEPT7; CDC42EP3; IGF2BP1; CDC42EP2; MAPK6; CDC42EP5; CDC42EP1B
    MAPK6/MAPK4 signaling MAPK4; CDC42EP1B; SEPT7; CDC42EP5; CDC42EP3; IGF2BP1; MAPK6; CDC42EP2
    MicroRNAs in cancer PIM1; SIRT1; EZR; HOXD10; GLS2; PDCD4; CCNE2; BAK1; SHC4; ERBB3
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription CBY1; CDX4; T; AES; TLE2; SALL4; HBP1; KRT1; TCF4; TLE1
    Signal Transduction BCO2A; OXGR1A.1; GDI2; ARHGAP32; NCKIPSD; ADH8A; BCO2L; WIPF2; RXFP2B; MLN

    igf2bp1 has several biochemical functions, for example, mRNA 3-UTR binding, mRNA 5-UTR binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by igf2bp1 itself. We selected most functions igf2bp1 had, and list some proteins which have the same functions with igf2bp1. You can find most of the proteins on our site.

    Function Related Protein
    mRNA 3-UTR binding CPEB3; CIRBP; IGF2BP1; RBM24; TARDBP; RBM24A; FXR1; RNF40; ELAVL4; PPP1R2P9
    mRNA 5-UTR binding IGF2BP2; IGF2BP1; MRPS11; IGF2BP3; DDX3X; RPS14; LARP1
    mRNA binding RC3H2; EDC3; EIF4A3; D19BWG1357E; AGO2; RBM5; QK; ELAVL1; CSTF2; CCDC55
    nucleotide binding KIF20B; GLULB; UBE2QL1; MRPL23; SNRNP35; CELF6; PDXK; PCXB; VDAC3; RAB12
    poly(A) RNA binding MRPL1; DAP3; RBM7; HSPB1; PPP1R2P9; MRPL54; EIF2S1B; FBL; SNW1; RBPMS
    protein binding POP7; VPS54; INTS3; EXOC3L; ANTXR2; CUL4A; GRK6; ABCE1; FBXO46; EBF1
    translation regulator activity RPS9; IGF2BP1; IGF2BP2; IGF2BP3; AIRE; RPS14; YBX2

    igf2bp1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with igf2bp1 here. Most of them are supplied by our site. Hope this information will be useful for your research of igf2bp1.

    PRKRA; HLA-B; GSK3B; ARHGDIA; CNBP; Ybx1; PSPH; ILK; IKBKE; SMYD2; LYAR; FTSJ1; PUF60; midostaurin; NS1; pre-let-7a

    Lederer, M; Bley, N; et al. The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer. SEMINARS IN CANCER BIOLOGY 29:3-12(2014).

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