Recombinant Human IRF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IRF3-4151H
• Product Overview: IRF3 MS Standard C13 and N15-labeled recombinant protein (NP_001562) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.2 kDa
• AA Sequence: MGTPKPRILPWLVSQLDLGQLEGVA WVNKSRTRFRIPWKHGLRQDAQQED FGIFQAWAEATGAYVPGRDKPDLPT WKRNFRSALNRKEGLRLAEDRSKDP HDPHKIYEFVNSGVGDFSQPDTSPD TNGGGSTSDTQEDILDELLGNMVLA PLPDPGPPSLAVAPEPCPQPLRSPS LDNPTPFPNLGPSENPLKRLLVPGE EWEFEVTAFYRGRQVFQQTISCPEG LRLVGSEVGDRTLPGWPVTLPDPGM SLTDRGVMSYVRHVLSCLGGGLALW RAGQWLWAQRLGHCHTYWAVSEELL PNSGHGPDGEVPKDKEGGVFDLGPF IVDLITFTEGSGRSPRYALWFCVGE SWPQDQPWTKRLVMVKVVPTCLRAL VEMARVGGASSLENTVDLHISNSHP LSLTSDQYKAYLQDLVEGMDFQGPG ESTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IRF3 interferon regulatory factor 3 [ Homo sapiens (human) ]
• Official Symbol: IRF3
• Synonyms: IRF3; interferon regulatory factor 3; IIAE7; interferon regulatory factor 3
• Gene ID: 3661
• mRNA Refseq: NM_001571
• Protein Refseq: NP_001562
• MIM: 603734
• UniProt ID: Q14653