Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

IRF7

  • Official Full Name

    interferon regulatory factor 7

  • Overview

    Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
  • Synonyms

    IRF7; interferon regulatory factor 7; IRF7A; IRF-7H; OTTHUMP00000162886; IRF-7; OTTHUMP00000162887; OTTHUMP00000229433; OTTHUMP00000229434; interferon regulatory factor-7H;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • Myc
  • DDK
  • Flag
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IRF7-896H Recombinant Human IRF7 Protein, His-tagged E.coli His
Human IRF7-5160HCL Recombinant Human IRF7 293 Cell Lysate HEK293 N/A
Human IRF7-1200H-B Recombinant Human IRF7 Protein Pre-coupled Magnetic Beads HEK293
Human IRF7-897H Recombinant Human IRF7 Protein, Myc/DDK-tagged HEK293T C-Myc/DDK
Human IRF7-1307HFL Recombinant Full Length Human IRF7 Protein, C-Flag-tagged Mammalian cells Flag
Human IRF7-825H Recombinant Human IRF7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF7-3116H Recombinant Human IRF7 protein E.coli N/A 1-503aa
Human IRF7-1200H Recombinant Human IRF7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Irf7-3578M Recombinant Mouse Irf7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque IRF7-2300R Recombinant Rhesus monkey IRF7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IRF7-2121R Recombinant Rhesus Macaque IRF7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IRF7-2121R-B Recombinant Rhesus Macaque IRF7 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish IRF7-10946Z Recombinant Zebrafish IRF7 Mammalian Cell His
Chicken IRF7-6924C Recombinant Chicken IRF7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IRF7 Related Articles

IRF7 involved in several pathways and played different roles in them. We selected most pathways IRF7 participated on our site, such as Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Toll-like receptor signaling pathwayTLR9;IFNPHI3;PIK3R1;MAPK1;MAPK8;IRF5;IFNA7;MYD88;FADD
RIG-I-like receptor signaling pathwayTBK1;IL-8;IKBKE;IFNE;MAP3K1;RNF125;IFNA2;IFNA12;TP-1
Cytosolic DNA-sensing pathwayPOLR3GL;POLR2H;IL6;Ifna11;IFNPHI1;POLR2F;NFKBIA;AIM2;IRF7
Hepatitis CIFNA2;SOCS3;CD81;EIF2AK4;TNFRSF1A;OAS1B;TYK2;MAPK10;CLDN6
Hepatitis BTGFB3;AKT1;CCNE2;AKT2;SMAD4;EGR3;PIK3R2;TBK1;BIRC5
MeaslesCD209B;IL1A;RCHY1;IL12A;CCND2;IRAK1;HSPA1L;TBK1;IFNA2
Influenza AACTB;HLA-DMA;OAS1A;Ifna15;AKT1;NUP98;IFNA7;ACTG1;PRKCB
Herpes simplex infectionSTAT1B;C3A.3;BF1;NXF1;PKZ;HLA-A;RNASEL;HCFC2;OAS1B
Viral carcinogenesisHLA-A;TP53;HDAC10;HIST1H4I;ATP6V0D1;MRPS18B;ACTN2;HIST2H2BB;SRC

IRF7 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRF7 itself. We selected most functions IRF7 had, and list some proteins which have the same functions with IRF7. You can find most of the proteins on our site.

Function Related Protein
DNA bindingIRX4A;IRF1B;PPARAA;ANG;MECP2;ZFP410;ASH1L;TXLNB;FOXA1
RNA polymerase II core promoter sequence-specific DNA bindingGATA1;GBX2;TP53;PAX8;SOX11;PAX6;H2AFY;RUNX2;HOXB3
protein bindingTXLNB;CREB5;NOXO1;CD79B;TMEM110;CLPTM1;CCDC86;GBP5;APOOL
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingSNAI3;RBPJB;FOSL1A;MSX2;ATF3;IRF7;JDP2;FOSB;FOSL1

IRF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRF7.

BICP0; ORF45; TBK1; AIP; LTN1; ARAF; IRAK1; TLK2

Audet, J; Kobinger, GP; et al. Immune Evasion in Ebolavirus Infections. VIRAL IMMUNOLOGY 28:10-18(2015).
Thackray, LB; Shrestha, B; et al. Interferon Regulatory Factor 5-Dependent Immune Responses in the Draining Lymph Node Protect against West Nile Virus Infection. JOURNAL OF VIROLOGY 88:11007-11021(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
05/27/2019

    Trusting in its consistent results, I am able to embark on my research with assurance and optimism.

    01/06/2017

      Its unwavering stability and functionality have significantly contributed to the success and validity of my experimental outcomes.

      03/31/2016

        I am profoundly impressed by the technical support rendered by the manufacturer.

        Ask a Question for All IRF7 Products

        Required fields are marked with *

        My Review for All IRF7 Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends