Recombinant Human IRF3 Protein, His-tagged

• Cat.No.: IRF3-072H
• Product Overview: Recombinant N-terminally Histidine-tagged full length human IRF3 protein (1-427) was purified from E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-427
• Description: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.
• Molecular Mass: 49.6 kDa
• Purity: ≥85% estimated by SDS-PAGE
• Stability: ≥ 1 year
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 8.0, 150 mM sodium chloride, and 10% glycerol

Gene Information

• Gene Name: IRF3 interferon regulatory factor 3 [ Homo sapiens (human) ]
• Official Symbol: IRF3
• Synonyms: IRF3; interferon regulatory factor 3; IIAE7; interferon regulatory factor 3
• Gene ID: 3661
• mRNA Refseq: NM_001571
• Protein Refseq: NP_001562
• MIM: 603734
• UniProt ID: Q14653