Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

IRF5

  • Official Full Name

    interferon regulatory factor 5

  • Overview

    This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
  • Synonyms

    IRF5; interferon regulatory factor 5; SLEB10; IRF-5; OTTHUMP00000212904; OTTHUMP00000212905; OTTHUMP00000212907; OTTHUMP00000212910;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Myc
  • DDK
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|SUMO
  • His|T7
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IRF5-5121H Recombinant Human IRF5, His-tagged E.coli His
Human IRF5-5162HCL Recombinant Human IRF5 293 Cell Lysate HEK293 N/A
Human IRF5-5163HCL Recombinant Human IRF5 293 Cell Lysate HEK293 N/A
Human IRF5-5164HCL Recombinant Human IRF5 293 Cell Lysate HEK293 N/A
Human IRF5-011H Recombinant Human IRF5 Protein, His-tagged E. coli His
Human IRF5-002H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-299H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-5740HF Recombinant Full Length Human IRF5 Protein, GST-tagged In Vitro Cell Free System GST 498 amino acids
Human IRF5-139H Recombinant Human IRF5 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human IRF5-007H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-593H Recombinant Human IRF5 protein, His-tagged E.coli His
Human IRF5-2694H Recombinant Human IRF5 Protein (Met1-Gln498), C-His tagged E.coli C-His Met1-Gln498
Human IRF5-936H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF5-009H Recombinant Human IRF5 Protein, His-tagged E. coli His
Human IRF5-595H Recombinant Human IRF5 protein, His-tagged E.coli His
Human IRF5-2695H Recombinant Human IRF5 Protein (Glu232-Ala477), N-His tagged E.coli N-His Glu232-Ala477
Human IRF5-001H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-3997H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF5-008H Recombinant Human IRF5 Protein, His-tagged E. coli His
Human IRF5-589H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-2228H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF5-4765H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF5-587H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-4865H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IRF5-588H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-555HFL Active Recombinant Full Length Human IRF5 Protein, C-Flag-tagged Mammalian cells Flag
Human IRF5-590H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-1198H Recombinant Human IRF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IRF5-591H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-1198H-B Recombinant Human IRF5 Protein Pre-coupled Magnetic Beads HEK293
Human IRF5-003H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-010H Recombinant Human IRF5 Protein, His-tagged E.coli His Tyr136~Ala475
Human IRF5-004H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-5037H Recombinant Human IRF5 Protein, GST-tagged Wheat Germ GST
Human IRF5-005H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-592H Recombinant Human IRF5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IRF5-006H Recombinant Human IRF5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human IRF5-3499H Recombinant Human IRF5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse IRF5-8303M Recombinant Mouse IRF5 Protein Mammalian Cell His
Mouse Irf5-7159M Recombinant Mouse Irf5 protein, His & T7-tagged E.coli His/T7 His3~Glu250 (Accession # P56477)
Mouse IRF5-4604M-B Recombinant Mouse IRF5 Protein Pre-coupled Magnetic Beads HEK293
Mouse Irf5-3576M Recombinant Mouse Irf5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse IRF5-4604M Recombinant Mouse IRF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Irf5-594M Recombinant Mouse Irf5 protein, Myc/DDK-tagged HEK293 Myc/DDK
Mouse Irf5-010M Recombinant Mouse Irf5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse IRF5-585M Recombinant Mouse IRF5 Protein (1-497 aa), His-SUMO-tagged E.coli His/SUMO 1-497 aa
Zebrafish IRF5-12134Z Recombinant Zebrafish IRF5 Mammalian Cell His
Chicken IRF5-3228C Recombinant Chicken IRF5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IRF5 Related Articles

IRF5 involved in several pathways and played different roles in them. We selected most pathways IRF5 participated on our site, such as Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Toll-like receptor signaling pathwayMAP2K4;PIK3R1;CD80;MAPK8;AKT1;MAPK8A;IKBKB;TICAM2;RAC1

IRF5 has several biochemical functions, for example, protein binding, regulatory region DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRF5 itself. We selected most functions IRF5 had, and list some proteins which have the same functions with IRF5. You can find most of the proteins on our site.

Function Related Protein
protein bindingTNFRSF11A;RABGGTB;SNX11;RSPH9;RG9MTD1;RNH1;PIM2;NOSTRIN;CD36
regulatory region DNA bindingIRF1B;NFKB1;IRF8;HMGA2;IRF6;IRF2A;IRF5;IRF1A;IRF3
transcription factor activity, sequence-specific DNA bindingTAL1;CLOCK;TBX24;ZNF155;TBX5;CARF;SKINT8;ZNF624;SLC30A9

IRF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRF5.

SGTA; RELA; MAVS; tnfa_human_isre1_dna-probe; TNF; GTPBP1; IRF6; PPM1G; CEP152; HIVEP1; RGS3

Ren, JY; Chen, X; et al. IKK beta is an IRF5 kinase that instigates inflammation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:17438-17443(2014).
AlFadhli, S; Jahabani, I; et al. Association of interferon regulatory factor 5 (IRF5) markers with an increased risk of lupus and overlapping autoimmunity in a Kuwaiti population. ANNALS OF HUMAN BIOLOGY 41:531-539(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All IRF5 Products

Required fields are marked with *

My Review for All IRF5 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends