Recombinant Human Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma)

• Cat.No.: PLA2G7-1744H
• Product Overview: Recombinant Human PLA2G7 wasexpressed in 293 cells.

Specification

• Cat. No.: PLA2G7-1744H
• Description: PLA2G7 is a secretedprotein that mediates PAF activity by specifically catalyzing hydrolysis ofthe "sn2" ester bond, resulting in the conversion of PAF to the biologicallyinactive lyso-PAF. PLA2G7 can also interact with LDL particles to induce thehydrolysis of LDL associated, oxidized phospholipids, generatinglysophosphatidylcholine (lyso-PC) and other lysophospholipids.
• Concentration: 10.0 ug/ml
• Source: Human
• Host: 293 cells
• Form: Suppliedas a lyophilized powder.
• Purity: > 95% pure by SDSPAGE and HPLC
• Sequence: Region of PLA2G7protein corresponding to amino acids: FDWQYINPVA HMKSSAWVNK IQVLMAAASFGQTKIPRGNG PYSVGCTDLM FDHTNKGTFL RLYYPSQDND RLDTLWIPNK EYFWGLSKFL GTHWLMGNILRLLFGSMTTP ANWNSPLRPG EKYPLVVFSH GLGAFRTLYS AIGIDLASHG FIVAAVEHRD RSASATYYFKDQSAAEIGDK SWLY.
• Molecular Mass: 47-55 kDa
• Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions.
• Storage: Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: PLA2G7

Gene Information

• Gene Name: PLA2G7 phospholipase A2, groupVII (platelet-activating factor acetylhydrolase, plasma) [ Homo sapiens]
• Synonyms: PLA2G7; phospholipaseA2, group VII (platelet-activating factor acetylhydrolase, plasma); PAFAH;LP-PLA2; LDL-PLA2; Platelet-activatingfactor acetylhydrolase; PAFacetylhydrolase; PAF 2-acylhydrolase; 1-alkyl-2-acetylglycerophosphocholineesterase; lipoprotein-associated phospholipase A2;2-acetyl-1-alkylglycerophosphocholine esterase; EC 3.1.1.47; Group-VIIA phospholipase A2; gVIIA-PLA2;LDL-associated phospholipase A2; LDL-PLA(2); EC 3.1.1; platelet-activating factoracetylhydrolase; OTTHUMP00000016555
• Gene ID: 7941
• mRNA Refseq: NM_001168357
• Protein Refseq: NP_001161829
• MIM: 601690
• UniProt ID: Q13093
• Chromosome Location: 6p21.2-p12
• Pathway: Ether lipid metabolism;Metabolic pathways; Diabetes pathways; Lissencephaly gene(LIS1) in neuronal migration and development, organism-specific biosystem; Synthesis,Secretion, and Deacylation of Ghrelin
• Function: 1-alkyl-2-acetylglycerophosphocholineesterase activity; hydrolase activity; phospholipid binding; calcium-independentphospholipase A2 activity