"PLA2G7" Related Products

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Recombinant Human Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma)

Cat. No.: PLA2G7-1744H
Product Overview: Recombinant Human PLA2G7 wasexpressed in 293 cells.
Description: PLA2G7 is a secretedprotein that mediates PAF activity by specifically catalyzing hydrolysis ofthe "sn2" ester bond, resulting in the conversion of PAF to the biologicallyinactive lyso-PAF. PLA2G7 can also interact with LDL particles to induce thehydrolysis of LDL associated, oxidized phospholipids, generatinglysophosphatidylcholine (lyso-PC) and other lysophospholipids.
Concentration: 10.0 ug/ml
Source: Human
Host: 293 cells
Form: Suppliedas a lyophilized powder.
Purity: > 95% pure by SDSPAGE and HPLC
Sequence: Region of PLA2G7protein corresponding to amino acids: FDWQYINPVA HMKSSAWVNK IQVLMAAASFGQTKIPRGNG PYSVGCTDLM FDHTNKGTFL RLYYPSQDND RLDTLWIPNK EYFWGLSKFL GTHWLMGNILRLLFGSMTTP ANWNSPLRPG EKYPLVVFSH GLGAFRTLYS AIGIDLASHG FIVAAVEHRD RSASATYYFKDQSAAEIGDK SWLY.
Molecular Mass: 47-55 kDa
Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions.
Storage: Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: PLA2G7
Gene Name: PLA2G7 phospholipase A2, groupVII (platelet-activating factor acetylhydrolase, plasma) [ Homo sapiens]
Synonyms: PLA2G7; phospholipaseA2, group VII (platelet-activating factor acetylhydrolase, plasma); PAFAH;LP-PLA2; LDL-PLA2; Platelet-activatingfactor acetylhydrolase; PAFacetylhydrolase; PAF 2-acylhydrolase; 1-alkyl-2-acetylglycerophosphocholineesterase; lipoprotein-associated phospholipase A2;2-acetyl-1-alkylglycerophosphocholine esterase; EC 3.1.1.47; Group-VIIA phospholipase A2; gVIIA-PLA2;LDL-associated phospholipase A2; LDL-PLA(2); EC 3.1.1; platelet-activating factoracetylhydrolase; OTTHUMP00000016555
Gene ID: 7941
mRNA Refseq: NM_001168357
Protein Refseq: NP_001161829
MIM: 601690
UniProt ID: Q13093
Chromosome Location: 6p21.2-p12
Pathway: Ether lipid metabolism;Metabolic pathways; Diabetes pathways; Lissencephaly gene(LIS1) in neuronal migration and development, organism-specific biosystem; Synthesis,Secretion, and Deacylation of Ghrelin
Function: 1-alkyl-2-acetylglycerophosphocholineesterase activity; hydrolase activity; phospholipid binding; calcium-independentphospholipase A2 activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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