Active Recombinant Mouse Tnfsf4, FLAG-tagged
Cat.No. : | Tnfsf4-407M |
Product Overview : | The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG-tag. |
- Specification
- Gene Information
- Related Products
Description : | OX40L [CD252; CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MegaOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation. |
Source : | HEK293 Cells |
Species : | Mouse |
Tag : | FLAG |
Form : | Lyophilized. Contains PBS. |
Bio-activity : | Activates T cell proliferation. |
Molecular Mass : | ~40kDa (SDS-PAGE) |
Purity : | ≥90% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 0.1mg/ml after reconstitution. |
Gene Name : | Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 [ Mus musculus ] |
Official Symbol : | Tnfsf4 |
Synonyms : | TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand superfamily member 4; OX40 ligand; atherosclerosis 1; tax-transcriptionally activated glycoprotein 1 ligand; Ath1; gp34; Ath-1; Ox40l; TXGP1; CD134L; OX-40L; Txgp1l; |
Gene ID : | 22164 |
mRNA Refseq : | NM_009452 |
Protein Refseq : | NP_033478 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cytokine activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor superfamily binding; |
Products Types
◆ Recombinant Protein | ||
TNFSF4-142H | Recombinant Human TNFSF4 Protein, His-tagged | +Inquiry |
TNFSF4-886M | Recombinant Mouse TNFSF4 Protein (Gln49-Leu198), MIgG1 Fc-tagged | +Inquiry |
TNFSF4-887M | Recombinant Mouse TNFSF4 Protein (Gln49-Leu198), RlgG Fc-tagged | +Inquiry |
Tnfsf4-6557M | Recombinant Mouse Tnfsf4 Protein, Myc/DDK-tagged | +Inquiry |
TNFSF4-5861R | Recombinant Rat TNFSF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFSF4-857CCL | Recombinant Cynomolgus TNFSF4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionGenetic changes in TNFSF4 affect immune regulation and autoimmune disease susceptibility.
TNFSF4 (OX40L) regulates immune responses and T-cell activation.
It activates T-cells, stimulating inflammatory cytokine production.
TNFSF4 is implicated in autoimmune disease development by promoting immune cell activation.
TNFSF4 interacts with OX40 and other receptors, influencing immune signaling.
Targeting TNFSF4 could treat autoimmune and inflammatory diseases by modulating the immune system.
Altered TNFSF4 activity contributes to chronic inflammation.
Customer Reviews (3)
Write a reviewEfficient service, accelerates research productivity.
Outstanding accuracy, essential for research quality.
Trusted for research integrity, a critical research asset.
Ask a Question for All Tnfsf4 Products
Required fields are marked with *
My Review for All Tnfsf4 Products
Required fields are marked with *
Inquiry Basket