Recombinant Chicken F7

• Cat.No.: F7-6012C
• Product Overview: Recombinant Chicken F7 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Chicken
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: F7 coagulation factor VII (serum prothrombin conversion accelerator) [ Gallus gallus (chicken) ]
• Official Symbol: F7
• Gene ID: 395086
• Protein Refseq: NP_989773
• UniProt ID: Q804X7

Reviews

05/18/2022

Quick turnaround—this product arrived swiftly, facilitating our research.

10/03/2019

Exceptional quality and precision—our lab relies on this protein consistently.

05/29/2018

Invaluable assistance from customer service—professional and responsive.

Q&As

How does F7 contribute to hemostasis, and what is its role in preventing excessive bleeding?

Factor VII's role in the coagulation cascade ensures rapid initiation of clot formation, preventing excessive bleeding and contributing to hemostasis.

Discuss the role of F7 in the extrinsic pathway of blood coagulation.

Factor VII is a key player in the extrinsic pathway, where it forms a complex with tissue factor to activate factor X, initiating the cascade leading to thrombin generation.

What are the mechanisms of F7 activation, and how is it regulated at the molecular level?

Factor VII is activated through a proteolytic cleavage, converting it into its active form (VIIa). This activation is regulated by tissue factor and other coagulation factors.

Explain the biochemical basis of F7 deficiency and its implications for bleeding disorders.

F7 deficiency results in impaired blood clotting, leading to a bleeding disorder known as coagulation factor VII deficiency. This condition can manifest in varying degrees of severity.

Explain the role of F7 in the coagulation cascade and blood clot formation.

Factor VII is activated to its enzymatically active form (factor VIIa) and initiates the coagulation cascade by activating factor X, ultimately leading to the formation of a stable blood clot.