|Official Full Name||coagulation factor XII|
|Background||Coagulation factor XII also known as Hageman factor is a plasma protein. It is the zymogen form of factor XIIa, an enzyme (EC 184.108.40.206) of the serine protease (or serine endopeptidase) class. In humans, factor XII is encoded by the F12 gene.|
|Synonyms||coagulation factor XII (Hageman factor); F12; HAF; HAE3; HAEX; coagulation factor XII; Hageman factor; OTTHUMP00000223845; beta-factor XIIa part 1; beta-factor XIIa part 2; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
f12 involved in several pathways and played different roles in them. We selected most pathways f12 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with f12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||C5; BDKRB2; PROC; C4A; F12; C1R; SERPIND1; SERPINA1; C8B; CD46|
f12 has several biochemical functions, for example, misfolded protein binding, protein binding, serine-type aminopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by f12 itself. We selected most functions f12 had, and list some proteins which have the same functions with f12. You can find most of the proteins on our site.
|misfolded protein binding||HDAC6; DNAJC3; DNAJC10; DNAJB9; SDF2L1; STUB1; BAG6; CLU; HSPD1; TOR1A|
|protein binding||TTPA; PSG5; EYA3; PHF20L1; PBX2; BCL2L16; LNX1; DICER1; GIT2; MYH7B|
|serine-type aminopeptidase activity||F12|
|serine-type endopeptidase activity||PRSS37; Prss32; GZMC; F11; MCPT8; KLK10; PRSS54; RHBDL3; KLK1B11; CMA1|
f12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f12 here. Most of them are supplied by our site. Hope this information will be useful for your research of f12.
KNG1; C1QBP; GP1BA