f7

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f7

Official Full Name coagulation factor VII (serum prothrombin conversion accelerator)
Background Factor VII (formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme (EC 3.4.21.21) of the serine protease class. A recombinant form of human factor VIIa (NovoSeven, eptacog alfa [activated]) has U.S. Food and Drug Administration approval for uncontrolled bleeding in hemophilia patients. It is often used unlicensed in severe uncontrollable bleeding, although there has been safety concerns.
Synonyms F7; coagulation factor VII; SPCA; eptacog alfa; proconvertin; OTTHUMP00000018733; OTTHUMP00000018734; FVII coagulation protein; serum prothrombin conversion accelerator; factor VII
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • Hamster Kidney
    • HEK293
    • HEK293T
    • Human Cell
    • Human Plasma
    • Mammalian Cell
    • NS0
    • Rabbit
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human F7-1911H Recombinant Human F7 protein, His-tagged E.coli His
    Human F7-1973HCL Recombinant Human F7 cell lysate Human Cell N/A
    Human F7-24H Human Blood Coagulation Factor VIIa Reference standard N/A
    Human F7-28711TH Recombinant Human F7 N/A
    Human F7-3622H Recombinant Human F7 Protein, GST-tagged Wheat Germ GST
    Human F7-3907H Recombinant Human F7, His tagged Human Cell His
    Human F7-39H Human Factor VII Reference standard N/A
    Human F7-5303H Native Human Coagulation Factor VII (serum prothrombin conversion accelerator) Human Plasma N/A
    Human F7-530H Recombinant Human F7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human F7-720H Recombinant Human F7 Protein, His-tagged NS0 His
    Human F7-959H Recombinant Human F7 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human F7-P042H Recombinant Human F7 therapeutic protein Hamster Kidney N/A
    Mouse CAB11538RM Rabbit Anti-Mouse FVII protein Monoclonal Antibody Rabbit N/A
    Mouse F7-001MCL Recombinant Mouse F7 cell lysate CHO N/A
    Mouse F7-1000M Recombinant Mouse F7 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse F7-1912M Recombinant Mouse F7 protein, His-tagged E.coli His
    Mouse F7-2206M Recombinant Mouse F7, His tagged CHO His
    Mouse F7-828M Recombinant Mouse F7 Protein, His-tagged CHO His
    Mouse F7-8662M Recombinant Mouse F7, His-tagged Human Cell His
    Rat F7-1913R Recombinant Rat F7 protein, His & GST-tagged E.coli His/GST
    Rat F7-1914R Recombinant Rat F7 protein, His-tagged E.coli His
    Rat F7-2180R Recombinant Rat F7 Protein Mammalian Cell His
    Rhesus Macaque F7-1532R Recombinant Rhesus monkey F7 Protein, His-tagged Mammalian Cell His
    Rabbit F7-1915R Recombinant Rabbit F7 protein, His & T7-tagged E.coli His/T7
    Chicken F7-6012C Recombinant Chicken F7 Mammalian Cell His
    Zebrafish F7-9330Z Recombinant Zebrafish F7 Mammalian Cell His
    Cattle F7-1910C Recombinant Cattle F7 protein, His & GST-tagged E.coli His/GST

    f7 involved in several pathways and played different roles in them. We selected most pathways f7 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with f7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Complement and coagulation cascades SERPINA1A; PROC; C8A; C4BPA; CD59A; THBD; SERPINF2; CR1L; MBL2; C5

    f7 has several biochemical functions, for example, calcium ion binding, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by f7 itself. We selected most functions f7 had, and list some proteins which have the same functions with f7. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCDH2G9; MMP10; EFHA2; EFCC1; MEX3B; S100A8; HPCAL4; CELSR1; PROCA; PTBP3
    glycoprotein binding IDE; FGFR1; THBS1; ERBB2; LACRT; FLNA; HSPA5; FOXRED2; IGF2R; F7
    protein binding DDA1; DEPDC6; LSM8; GEMIN7; MYC; RNF32; GNMT; DPP4; IGF2BP1; PHF15
    receptor binding SSFA2; CD72; UFD1L; ADCYAP1; GNPAT; P2RX7; TGFB2; FZD8; HAND2; POU2F1
    serine-type endopeptidase activity PIK3IP1; DPP4; F9B; RHBDD2; IMMP1L; PRSS44; F9; C1RL; CELA3A; KLK15
    serine-type peptidase activity PRSS30; F7; KLK1B8; PCSK5B; HTRA1A; ELA3L; PRSS48; ENDOU; HTRA3; GZMC

    f7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f7 here. Most of them are supplied by our site. Hope this information will be useful for your research of f7.

    F3; capsh_ade05; DMWD; USP49; UIMC1; IKBKG; RCHY1; ALB; BECN1; SLX4; GABARAPL1

    Guo, HJ; Cruz-Munoz, ME; et al. Immune Cell Inhibition by SLAMF7 Is Mediated by a Mechanism Requiring Src Kinases, CD45, and SHIP-1 That Is Defective in Multiple Myeloma Cells. MOLECULAR AND CELLULAR BIOLOGY 35:41-51(2015).
    Balasa, B; Yun, R; et al. Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-alpha pathways. CANCER IMMUNOLOGY IMMUNOTHERAPY 64:61-73(2015).

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