|Official Full Name||coagulation factor VII (serum prothrombin conversion accelerator)|
|Background||Factor VII (formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme (EC 126.96.36.199) of the serine protease class. A recombinant form of human factor VIIa (NovoSeven, eptacog alfa [activated]) has U.S. Food and Drug Administration approval for uncontrolled bleeding in hemophilia patients. It is often used unlicensed in severe uncontrollable bleeding, although there has been safety concerns.|
|Synonyms||F7; coagulation factor VII; SPCA; eptacog alfa; proconvertin; OTTHUMP00000018733; OTTHUMP00000018734; FVII coagulation protein; serum prothrombin conversion accelerator; factor VII|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
f7 involved in several pathways and played different roles in them. We selected most pathways f7 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with f7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||SERPINA1A; PROC; C8A; C4BPA; CD59A; THBD; SERPINF2; CR1L; MBL2; C5|
f7 has several biochemical functions, for example, calcium ion binding, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by f7 itself. We selected most functions f7 had, and list some proteins which have the same functions with f7. You can find most of the proteins on our site.
|calcium ion binding||PCDH2G9; MMP10; EFHA2; EFCC1; MEX3B; S100A8; HPCAL4; CELSR1; PROCA; PTBP3|
|glycoprotein binding||IDE; FGFR1; THBS1; ERBB2; LACRT; FLNA; HSPA5; FOXRED2; IGF2R; F7|
|protein binding||DDA1; DEPDC6; LSM8; GEMIN7; MYC; RNF32; GNMT; DPP4; IGF2BP1; PHF15|
|receptor binding||SSFA2; CD72; UFD1L; ADCYAP1; GNPAT; P2RX7; TGFB2; FZD8; HAND2; POU2F1|
|serine-type endopeptidase activity||PIK3IP1; DPP4; F9B; RHBDD2; IMMP1L; PRSS44; F9; C1RL; CELA3A; KLK15|
|serine-type peptidase activity||PRSS30; F7; KLK1B8; PCSK5B; HTRA1A; ELA3L; PRSS48; ENDOU; HTRA3; GZMC|
f7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f7 here. Most of them are supplied by our site. Hope this information will be useful for your research of f7.
F3; capsh_ade05; DMWD; USP49; UIMC1; IKBKG; RCHY1; ALB; BECN1; SLX4; GABARAPL1