|Official Full Name||F11 receptor|
|Background||Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.|
|Synonyms||F11R; F11 receptor; JAM1, junctional adhesion molecule 1; junctional adhesion molecule A; CD321; JAM 1; JAM A; JAMA; JCAM; PAM 1; platelet F11 receptor; platelet adhesion molecule 1; junctional adhesion molecule 1; JAM; KAT; JAM1; PAM-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
f11r involved in several pathways and played different roles in them. We selected most pathways f11r participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with f11r were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||CDH4; NLGN4A; CD40LG; Icosl; CD274; NLGN2; ESAM; HLA-DPA1; CD6; CD40|
|Tight junction||PPP2R2CA; CLDN5A; MYL12.1; CLDN11B; CDC42L2; CRB3A; ACTN2B; RHOAC; HRASA; CLDNF|
|Leukocyte transendothelial migration||PRKCA; ACTN3; THY1; VASP; CYBA; CLDN20; PIK3R5; CLDN23; VAV2; ITGB1|
|Epithelial cell signaling in Helicobacter pylori infection||MAPK11; ATP6V1G3; TJP1; MET; ATP6V1C2; LYN; ATP6V0A4; IKBKG; GIT1; ATP6V1H|
f11r has several biochemical functions, for example, PDZ domain binding, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by f11r itself. We selected most functions f11r had, and list some proteins which have the same functions with f11r. You can find most of the proteins on our site.
|PDZ domain binding||SLC9A3; PSEN1; FZD8; LPAR1; DLC; KIDINS220; SDC2; CIT; FZD2; Apba1|
|protein binding||KLRC1; PRUNE; KCNK16; FAM49B; PNKP; C4orf26; ANXA9; AP2S1; ICAM3; EDEM1|
|virus receptor activity||PVRL4; SLAMF1; EFNB3; CD4; CCR5; HTR2A; DPP4; CR1; TNFRSF4; CD209A|
f11r has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f11r here. Most of them are supplied by our site. Hope this information will be useful for your research of f11r.
SGTA; PRKCZ; PARD3; BDNF; PEX19; CASK