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Official Full Name coagulation factor XI
Background Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene.
Synonyms coagulation factor XI; F11; FXI; MGC141891; PTA; OTTHUMP00000197033; plasma thromboplastin antecedent
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human plasma
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human F11-178H Human Blood Coagulation Factor XI Reference standard N/A
    Human F11-1861H Recombinant Human F11 protein, His & T7-tagged E.coli His/T7
    Human F11-2004H Recombinant Human F11 Protein (19-387 aa), His-tagged E.coli His
    Human F11-2466H Native Human Coagulation Factor XI Human plasma N/A
    Human F11-2681HCL Recombinant Human F11 cell lysate Human Cell N/A
    Human F11-290H Recombinant Human F11, His tagged Human Cell His
    Human F11-3602H Recombinant Human F11 Protein, GST-tagged Wheat Germ GST
    Human F11-42H Factor XI Reference standard N/A
    Human F11-957H Recombinant Human F11 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse F11-439M Recombinant Mouse F11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse F11-5404M Recombinant Mouse F11 Protein Mammalian Cell His
    Mouse F11-766M Recombinant Mouse F11 Protein, His-tagged NS0 His
    Mouse F11-900M Recombinant Mouse F11 Protein, His-tagged E. coli His
    Rat F11-1862R Recombinant Rat F11 protein, His & GST-tagged E.coli His/GST

    f11 involved in several pathways and played different roles in them. We selected most pathways f11 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with f11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Complement and coagulation cascades F13A1; C1RA; Serpina1b; C3AR1; MBL2; Serpina1c; F3; C1R; MASP2; PLAT

    f11 has several biochemical functions, for example, heparin binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by f11 itself. We selected most functions f11 had, and list some proteins which have the same functions with f11. You can find most of the proteins on our site.

    Function Related Protein
    heparin binding PLA2G5; MSTN; BMP4; ADAMTSL5; ITGAM; LRPAP1; FMOD; FGF14; FGFR1; THBS4
    protein binding OSBP; MYBL2; SYT4; PRAC; COL8A1; 2610109H07Rik; FANCF; ZCCHC17; MED1; NME2
    serine-type endopeptidase activity ST14B; OVCH2; C1RA; PRSS22; KLK4; TMPRSS13B; TRY; HGF; PCSK1; EGFBP2

    f11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f11 here. Most of them are supplied by our site. Hope this information will be useful for your research of f11.


    Gonzalez-Burgos, E; Fernandez-Moriano, C; et al. Potential Neuroprotective Activity of Ginseng in Parkinson's Disease: A Review. JOURNAL OF NEUROIMMUNE PHARMACOLOGY 10:14-29(2015).
    Bruzelius, M; Bottai, M; et al. Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13:219-227(2015).

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