|Official Full Name||coagulation factor XI|
|Background||Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene.|
|Synonyms||coagulation factor XI; F11; FXI; MGC141891; PTA; OTTHUMP00000197033; plasma thromboplastin antecedent|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
f11 involved in several pathways and played different roles in them. We selected most pathways f11 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with f11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||F13A1; C1RA; Serpina1b; C3AR1; MBL2; Serpina1c; F3; C1R; MASP2; PLAT|
f11 has several biochemical functions, for example, heparin binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by f11 itself. We selected most functions f11 had, and list some proteins which have the same functions with f11. You can find most of the proteins on our site.
|heparin binding||PLA2G5; MSTN; BMP4; ADAMTSL5; ITGAM; LRPAP1; FMOD; FGF14; FGFR1; THBS4|
|protein binding||OSBP; MYBL2; SYT4; PRAC; COL8A1; 2610109H07Rik; FANCF; ZCCHC17; MED1; NME2|
|serine-type endopeptidase activity||ST14B; OVCH2; C1RA; PRSS22; KLK4; TMPRSS13B; TRY; HGF; PCSK1; EGFBP2|
f11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with f11 here. Most of them are supplied by our site. Hope this information will be useful for your research of f11.