Recombinant Human KDR Protein, Strep-tagged
Cat.No. : | KDR-476H |
Product Overview : | Recombinant human KDR protein with Strep tag was expressed in HEK293. |
- Specification
- Gene Information
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Description : | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Source : | HEK293 |
Species : | Human |
Tag : | Strep |
Form : | Lyophilized |
Molecular Mass : | 86.3 kDa |
Protein Length : | 1356 |
AA Sequence : | MQSKVLLAVALWLCVETRAASVGLP SVSLDLPRLSIQKDILTIKANTTLQ ITCRGQRDLDWLWPNNQSGSEQRVE VTECSDGLFCKTLTIPKVIGNDTGA YKCFYRETDLASVIYVYVQDYRSPF IASVSDQHGVVYITENKNKTVVIPC LGSISNLNVSLCARYPEKRFVPDGN RISWDSKKGFTIPSYMISYAGMVFC EAKINDESYQSIMYIVVVVGYRIYD VVLSPSHGIELSVGEKLVLNCTART ELNVGIDFNWEYPSSKHQHKKLVNR DLKTQSGSEMKKFLSTLTIDGVTRS DQGLYTCAASSGLMTKKNSTFVRVH EKPFVAFGSGMESLVEATVGERVRI PAKYLGYPPPEIKWYKNGIPLESNH TIKAGHVLTIMEVSERDTGNYTVIL TNPISKEKQSHVVSLVVYVPPQIGE KSLISPVDSYQYGTTQTLTCTVYAI PPPHHIHWYWQLEEECANEPSQAVS VTNPYPCEEWRSVEDFQGGNKIEVN KNQFALIEGKNKTVSTLVIQAANVS ALYKCEAVNKVGRGERVISFHVTRG PEITLQPDMQPTEQESVSLWCTADR STFENLTWYKLGPQPLPIHVGELPT PVCKNLDTLWKLNATMFSNSTNDIL IMELKNASLQDQGDYVCLAQDRKTK KRHCVVRQLTVLERVAPTITGNLEN QTTSIGESIEVSCTASGNPPPQIMW FKDNETLVEDSGIVLKDGNRNLTIR RVRKEDEGLYTCQACSVLGCAKVEA FFIIEGAQEKTNLEIIILVGTAVIA MFFWLLLVIILRTVKRANGGELKTG YLSIVMDPDELPLDEHCERLPYDAS KWEFPRDRLKLGKPLGRGAFGQVIE ADAFGIDKTATCRTVAVKMLKEGAT HSEHRALMSELKILIHIGHHLNVVN LLGACTKPGGPLMVIVEFCKFGNLS TYLRSKRNEFVPYKTKGARFRQGKD YVGAIPVDLKRRLDSITSSQSSASS GFVEEKSLSDVEEEEAPEDLYKDFL TLEHLICYSFQVAKGMEFLASRKCI HRDLAARNILLSEKNVVKICDFGLA RDIYKDPDYVRKGDARLPLKWMAPE TIFDRVYTIQSDVWSFGVLLWEIFS LGASPYPGVKIDEEFCRRLKEGTRM RAPDYTTPEMYQTMLDCWHGEPSQR PTFSELVEHLGNLLQANAQQDGKDY IVLPISETLSMEEDSGLSLPTSPVS CMEEEEVCDPKFHYDNTAGISQYLQ NSKRKSRPVSVKTFEDIPLEEPEVK VIPDDNQTDSGMVLASEELKTLEDR TKLSPSFGGMVPSKSRESVASEGSN QTSGYQSGYHSDDTDTTVYSSEEAE LLKLIEIGVQTGSTAQILQPDSGTT LSSPPV |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name : | KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens (human) ] |
Official Symbol : | KDR |
Synonyms : | KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; |
Gene ID : | 3791 |
mRNA Refseq : | NM_002253 |
Protein Refseq : | NP_002244 |
MIM : | 191306 |
UniProt ID : | P35968 |
Products Types
◆ Lysates | ||
KDR-1520MCL | Recombinant Mouse KDR cell lysate | +Inquiry |
KDR-417HCL | Recombinant Human KDR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1609 | KDR Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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