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Recombinant Human KDR Protein, His-tagged

Cat.No. : KDR-070H
Product Overview : Recombinant protein from the second and third Ig-like C2-type domains (D120-T320) of homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) (NM_002253), with a polyhistidine tag was expressed in human cells.
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Description : Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Source : Human cells
Species : Human
Tag : His
Molecular Mass : 25.1 kDa
Endotoxin : Endotoxin level is < 0.1 ng/μg of protein (< 1 EU /μg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Storage Buffer : Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Gene Name : KDR kinase insert domain receptor [ Homo sapiens (human) ]
Official Symbol : KDR
Synonyms : KDR; kinase insert domain receptor; FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; fetal liver kinase-1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; EC 2.7.10.1
Gene ID : 3791
mRNA Refseq : NM_002253
Protein Refseq : NP_002244
MIM : 191306
UniProt ID : P35968

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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