| Description : |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
| Source : |
HEK293 |
| Species : |
Rhesus macaque |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
85.2 kDa |
| Protein Length : |
1356 |
| AA Sequence : |
MASKVLLAVALWLCVETRAASVGLP SVSLDLPRLSIQKDILTIKANTTLQ ITCRGQRDLDWLWPNNQSGSEQRVE VTECSDGLFCKTLTIPKVIGNDTGA YKCFYRETDLASVIYVYVQDYRSPF IASVSDQHGVVYITENKNKTVVIPC LGSISNLNVSLCARYPEKRFVPDGN RISWDSKKGFTIPSYMISYAGMVFC EAKINDESYQSIMYIVVVVGYRIYD VVLSPSHGVELSVGEKLVLNCTART ELNVGIDFNWEYPSSKHQHKKLVNR DLKTQSGSEMKKFLSTLTIDGVTRS DQGLYTCAASSGLMTKKNSTFVRVH EKPFVAFGSGMESLVEATVGERVRI PVKYLGYPPPEIKWYKNGIPLESNH TVKVGHVLTIMEVSERDTGNYTVIL TNPISKEKQSHVVSLVVYVPPQIGE KSLISPVDSYQYGTTQTLTCTVYAI PPPHHIHWYWQLEEECPNEPSQAVS VTNPYPCEEWRSVEDFQGGNKIEVN KNQFALIEGKNKTVSTLVIQAANVS ALYKCEAVNKVGRGERVISFHVTRG PEITLQPDLQPTEQESVSLWCTADK STFENLTWYKLGPQPLPVHVGELPT PVCKNLDTLWKLNATIFSNSTNDIL IMELKNASLQDQGDYVCVAQDRKTK KRHCVVRQLTVLERVAPMITGNLEN QTTSIGETIEVSCTASGNPPPQIMW FKDNETLVEDSGIVLKDGNRNLTIR RVRKEDEGLYTCQACSVLGCAKVEA FFIIEGAQEKTNLEIIILVGTAVIA MFFWLLLVIILRTVKRANGGELKTG YLSIVMDPDELPLDEHCERLPYDAS KWEFPRDRLKLGKPLGRGAFGQVIE ADAFGIDKTATCRTVAVKMLKEGAT HSEHRALMSELKILIHIGHHLNVVN LLGACTKPGGPLMVIVEFCKFGNLS TYLRSKRNEFVPYKTKGARFRQGKD YVGAIPVDLKRRLDSITSSQSSASS GFVEEKSLSDVEEEEAPEDLYKDFL TLEHLICYSFQVAKGMEFLASRKCI HRDLAARNILLSEKNVVKICDFGLA RDIYKDPDYVRKGDARLPLKWMAPE TIFDRVYTIQSDVWSFGVLLWEIFS LGASPYPGVKIDEEFCRRLKEGTRM RAPDYTTPEMYQTMLDCWHGEPSQR PTFSELVEHLGNLLQANAQQDGKDY IVLPISETLSMEEDSGLSLPTSPVS CMEEEEVCDPKFHYDNTAGISQYLQ NSKRKSRPVSVKTFEDIPLEEPEVK VIPDDNQTDSGMVLASEELKTLEDR TKLAPSFSGMVSSKSRESVASEGSN QTSGYQSGYHSDDTDTTVYSSEEAE LLKLIEIGVQTGSTAQILQPDSGTT LSSPPV |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
