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Recombinant Human UBE2Z, His-tagged

Cat.No.: UBE2Z-233H
Product Overview: UBE2Z, 1-246aa, Human, His tag, E.coli
Description: UBE2z belongs to the ubiquitin-conjugating enzyme family. This protein catalyzes the covalent attachment of ubiquitin to other proteins. It is a specific substrate for UBA6, not charged with ubiquitin by UBE1 and may be involved in apoptosis regulation. Recombinant human UBE2Z protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Molecular Mass: 30.5 kDa (269aa), confirmed by MALDI-TOF
Protein length: 1-246aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSIYKEP PPGMFVVPDT VDMTKIHALI TGPFDTPYEG GFFLFVFRCP PDYPIHPPRV KLMTTGNNTV RFNPNFYRNG KVCLSILGTW TGPAWSPAQS ISSVLISIQS LMTENPYHNE PGFEQERHPG DSKNYNECIR HETIRVAVCD MMEGKCPCPE PLRGVMEKSF LEYYDFYEVA CKDRLHLQGQ TMQDPFGEKR GHFDYQSLLM RLGLIRQKVL ERLHNENAEM DSDSSSSGTE TDLHGSLRV
Purity: >95% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: UBE2Z ubiquitin-conjugating enzyme E2Z [ Homo sapiens ]
Official Symbol: UBE2Z
Synonyms: UBE2Z; ubiquitin-conjugating enzyme E2Z; ubiquitin-conjugating enzyme E2 Z; FLJ13855; UBA6 specific enzyme E2; USE1; UBA6-specific enzyme E2; ubiquitin-protein ligase Z; ubiquitin carrier protein Z; uba6-specific E2 conjugating enzyme 1; HOYS7;
Gene ID: 65264
mRNA Refseq: NM_023079
Protein Refseq: NP_075567
MIM: 611362
UniProt ID: Q9H832
Chromosome Location: 17q21.32
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function: ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin-protein ligase activity;

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