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UBE2C

  • Official Full Name

    ubiquitin-conjugating enzyme E2C

  • Overview

    UbcH10 in conjunction with the anaphase-promoting complex catalyzes the destruction of cyclins A and B and therefore plays an important role in the control of the cell exit from mitosis.
  • Synonyms

    UBE2C; ubiquitin-conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; UBCH10; ubiquitin-protein ligase C; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme; dJ447F3.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Met|His
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UBE2C-899H Active Recombinant Human UBE2C Protein, Met & His-tagged E.coli Met/His
Human UBE2C-643H Active Recombinant Human UBE2C Protein, His-tagged E.coli His
Human UBE2C-900H Active Recombinant Human UBE2C E.coli N/A
Human UBE2C-10H Recombinant Human Ubiquitin Conjugating Enzyme 10,His-tagged E.coli His
Human UBE2C-04H Recombinant Human UBE2C protein E.coli N/A 191
Human UBE2C-118H Recombinant Human UBE2C E.coli N/A
Human UBE2C-3527H Recombinant Human UBE2C, GST-tagged E.coli GST 1-179aa
Human UBE2C-221H Recombinant Human UBE2C, His-tagged E.coli His
Human UBE2C-591HCL Recombinant Human UBE2C 293 Cell Lysate HEK293 N/A
Human UBE2C-592HCL Recombinant Human UBE2C 293 Cell Lysate HEK293 N/A
Human UBE2C-5732H Recombinant Human UBE2C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UBE2C-0029H Recombinant Human UBE2C Protein (A2-P179), Tag Free Insect Cell No tag A2-P179
Human UBE2C-5854H Recombinant Human UBE2C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UBE2C-5587H Recombinant Human UBE2C Protein (Ala2-Pro179), N-His tagged E.coli N-His Ala2-Pro179
Human UBE2C-2295H Recombinant Human UBE2C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human UBE2C-792HFL Recombinant Full Length Human UBE2C Protein, C-Flag-tagged Mammalian cells Flag
Human UBE2C-0030H Recombinant Human UBE2C Protein (A2-P179), His/Strep tagged Insect Cell His/Strep A2-P179
Human UBE2C-2295H-B Recombinant Human UBE2C Protein Pre-coupled Magnetic Beads HEK293
Mouse Ube2c-6781M Recombinant Mouse Ube2c Protein, Myc/DDK-tagged HEK293T Myc/DDK
Cynomolgus Monkey UBE2C-1072C Recombinant Cynomolgus UBE2C Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey UBE2C-815C Recombinant Cynomolgus Monkey UBE2C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey UBE2C-815C-B Recombinant Cynomolgus Monkey UBE2C Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UBE2C-3585Z Recombinant Zebrafish UBE2C Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

UBE2C involved in several pathways and played different roles in them. We selected most pathways UBE2C participated on our site, such as APC-Cdc20 mediated degradation of Nek2A, APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Cyclin B, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
APC-Cdc20 mediated degradation of Nek2AUBE2C;NEK2;ANAPC10
APC/C-mediated degradation of cell cycle proteinsCDK2;ANAPC10;NEK2;UBE2C;AURKB;PSMD5;PSMD10;PSMD9;PSMA8
APC/C:Cdc20 mediated degradation of Cyclin BANAPC10;UBE2C
APC/C:Cdc20 mediated degradation of SecurinPSMD9;PSMD14;ANAPC10;PSMD5;PSMD10;UBE2C;PSME3;PSMA8
APC/C:Cdc20 mediated degradation of mitotic proteinsPSMD9;UBE2C;PSME3;PSMD10;PSMD5;PSMD14;ANAPC10;NEK2;PSMA8
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1PSMD5;PSMD9;PSMD10;ANAPC10;UBE2C;AURKB;PSMA8;PSMD14;PSME3
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpointUBE2C;PSMD9;ANAPC10;PSMD14;PSMA8;PSMD10;PSMD5;NEK2;PSME3
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsPSMD10;PSME3;PSMD5;PSMD14;UBE2C;NEK2;PSMD9;ANAPC10;PSMA8

UBE2C has several biochemical functions, for example, ATP binding, protein binding, ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2C itself. We selected most functions UBE2C had, and list some proteins which have the same functions with UBE2C. You can find most of the proteins on our site.

Function Related Protein
ATP bindingATP12A;CDC6;MUSK;ATP6V1B1;CDKL2;MTPAP;ATP5A1;ACTG1;BRIP1
protein bindingS100A16;ANXA9;TNNI2;TOR1B;NBR1;RPL23A;EIF3G;KIF23;HAND2
ubiquitin conjugating enzyme activityUBE2E1;UBE2V2;UBE2G1;UBE2QL1;CDC34;UBE2O;UBE2N;UBE2Z;UBE2D3
ubiquitin protein ligase activityRNF19A;RNF121;FBXO30;UBE2W;TRIM71;RNF144A;MSL2;RBBP6;WWP2
ubiquitin protein ligase bindingPOLR2A;TRIB3;GPI;GPR19;ERLIN2;CUL5;DNM1L;PRKAR2A;TANK
ubiquitin-protein transferase activitySIAH1;UBA7;RNF144B;TRIP12;CNOT4B;MIB2;UBE2G2;TRIM33;RNF220
contributes_to ubiquitin-protein transferase activityKBTBD11;CCIN;CUL3;KLHL13;GAN;DBN1;KLHL32;TCEB3B;KLHL2

UBE2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2C here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2C.

UBE2V1; ENO2; CXCR1; TNNC1; PCGF3; DTX1; RANBP9; EBNA1BP2; P

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