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Official Full Name ubiquitin-conjugating enzyme E2 variant 2
Background Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.
Synonyms UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; DDVit 1; EDPF 1; MMS2; UEV 2; 1 alpha 25 dihydroxyvitamin D3 inducible; 1 alpha 25-dihydroxyvitamin D3 inducible; DDVIT1; EDAF-1; EDAF1; EDPF-1; EDPF1; Enterocyte differentiation associated factor EDAF 1; Enterocyte differentiation promoting factor; Enterocyte differentiation-associated factor 1; Enterocyte differentiation-promoting factor 1; Methyl methanesulfonate sensitive 2; MMS 2; MMS2 homolog; UB2V2_HUMAN; UBE2V 2; Ubiquitin conjugating enzyme E2 variant 2; Ubiquitin conjugating enzyme E2v2; UEV2; Vitamin D3 inducible protein; Vitamin D3-inducible protein; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation-associated factor EDAF-1; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of; UEV-2; DDVit-1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2V2-143H Recombinant Human UBE2V2 E.coli N/A
    Human UBE2V2-210H Recombinant Human UBE2V2, His-tagged E.coli His
    Human UBE2V2-30036TH Recombinant Human UBE2V2, His-tagged E.coli His
    Human UBE2V2-559HCL Recombinant Human UBE2V2 293 Cell Lysate HEK293 N/A
    Human UBE2V2-60H Recombinant Human UBE2V2, His-tagged E.coli His
    Mouse UBE2V2-17736M Recombinant Mouse UBE2V2 Protein Mammalian Cell His
    Rhesus Macaque UBE2V2-5069R Recombinant Rhesus monkey UBE2V2 Protein, His-tagged Mammalian Cell His
    Chicken UBE2V2-2699C Recombinant Chicken UBE2V2 Mammalian Cell His
    Zebrafish UBE2V2-12674Z Recombinant Zebrafish UBE2V2 Mammalian Cell His

    ube2v2 involved in several pathways and played different roles in them. We selected most pathways ube2v2 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ube2v2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CD200R2; AP1G1; CLEC2H; IGHM; RNF19B; CXADR; RAP1GAP2; AGO1; KIF2C; CD200R4
    Antigen processing: Ubiquitination &amp LTN1; TRIM69; DZIP3; SPSB2; DTX3L; ASB10; ARIH2; UBE2U; RNF111; PJA1
    Proteasome degradation UBR2; RNF182; FBXO17; ASB10; TRIM69; SPSB4; VPRBP; RNF34; TRIM11; IWS1
    Cell Cycle SPC24; TMEM188; THRSP; MCM6L; MCM6; ANAPC5; E2F3; MSH5; DHFR; DYRK1A
    Cell Cycle Checkpoints HIST3H2BB; CHEK1; BARD1; RAD50; RNF168; THRSP; BRCC3; CHEK2; MCM8; HTATIP
    Class I MHC mediated antigen processing &amp PJA2; SEC23A; LTN1; TRIM69; CTSS; UBE2E3; ASB6; WWP1; TRIM50; CMTM2A
    presentation ATG7; UBR1; VPRBP; TRIM69; FBXO27; CYBB; TPP2; UBE2J2; RNF34; FBXO17
    DNA Double Strand Break Response UBE2V2; BRCC3; BABAM1; UIMC1; FAM175A; RAD50; CHEK2; BARD1; SMARCA5; HTATIP
    DNA Double-Strand Break Repair GEN1; BRCC3; EYA3; PPP4CB; PPP4R2B; DNA2; RAD9B; CLSPN; PPP4R2A; UBE2V2

    ube2v2 has several biochemical functions, for example, protein binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ube2v2 itself. We selected most functions ube2v2 had, and list some proteins which have the same functions with ube2v2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PPP4R4; UBL7; KIF14; NRCAM; NRG4; MRE11A; GPR85; G3BP2; PLG; VPS4A
    ubiquitin conjugating enzyme activity UBE2E2; UBE2D1; UBE2A; UBE2Z; UBE2C; UBE2V1; UBE2D2A; UBE2Q1; UBE2QL1; UBE2H
    ubiquitin protein ligase activity SIAH1; C18orf25; PRPF19; ZSWIM2; ASB4; CDC34A; ZNRF2; CDC42; RNF7; TRAF6
    ubiquitin protein ligase binding GABARAPL2; SLC22A18; UBE2L3; TRIM37; RPA2; RPA3; RANGAP1; UQCRC1; CUL5; TRIM28

    ube2v2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ube2v2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ube2v2.


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