|Official Full Name||ubiquitin-conjugating enzyme E2 variant 2|
|Background||Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.|
|Synonyms||UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; DDVit 1; EDPF 1; MMS2; UEV 2; 1 alpha 25 dihydroxyvitamin D3 inducible; 1 alpha 25-dihydroxyvitamin D3 inducible; DDVIT1; EDAF-1; EDAF1; EDPF-1; EDPF1; Enterocyte differentiation associated factor EDAF 1; Enterocyte differentiation promoting factor; Enterocyte differentiation-associated factor 1; Enterocyte differentiation-promoting factor 1; Methyl methanesulfonate sensitive 2; MMS 2; MMS2 homolog; UB2V2_HUMAN; UBE2V 2; Ubiquitin conjugating enzyme E2 variant 2; Ubiquitin conjugating enzyme E2v2; UEV2; Vitamin D3 inducible protein; Vitamin D3-inducible protein; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation-associated factor EDAF-1; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of; UEV-2; DDVit-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ube2v2 involved in several pathways and played different roles in them. We selected most pathways ube2v2 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ube2v2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||CD200R2; AP1G1; CLEC2H; IGHM; RNF19B; CXADR; RAP1GAP2; AGO1; KIF2C; CD200R4|
|Antigen processing: Ubiquitination &||LTN1; TRIM69; DZIP3; SPSB2; DTX3L; ASB10; ARIH2; UBE2U; RNF111; PJA1|
|Proteasome degradation||UBR2; RNF182; FBXO17; ASB10; TRIM69; SPSB4; VPRBP; RNF34; TRIM11; IWS1|
|Cell Cycle||SPC24; TMEM188; THRSP; MCM6L; MCM6; ANAPC5; E2F3; MSH5; DHFR; DYRK1A|
|Cell Cycle Checkpoints||HIST3H2BB; CHEK1; BARD1; RAD50; RNF168; THRSP; BRCC3; CHEK2; MCM8; HTATIP|
|Class I MHC mediated antigen processing &||PJA2; SEC23A; LTN1; TRIM69; CTSS; UBE2E3; ASB6; WWP1; TRIM50; CMTM2A|
|presentation||ATG7; UBR1; VPRBP; TRIM69; FBXO27; CYBB; TPP2; UBE2J2; RNF34; FBXO17|
|DNA Double Strand Break Response||UBE2V2; BRCC3; BABAM1; UIMC1; FAM175A; RAD50; CHEK2; BARD1; SMARCA5; HTATIP|
|DNA Double-Strand Break Repair||GEN1; BRCC3; EYA3; PPP4CB; PPP4R2B; DNA2; RAD9B; CLSPN; PPP4R2A; UBE2V2|
|DNA Repair||RBBP8; INO80B; BAZ1B; TDP1; PPIE; DCLRE1A; RAD18; USP10; THRSP; KDM4A|
ube2v2 has several biochemical functions, for example, protein binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ube2v2 itself. We selected most functions ube2v2 had, and list some proteins which have the same functions with ube2v2. You can find most of the proteins on our site.
|protein binding||PPP4R4; UBL7; KIF14; NRCAM; NRG4; MRE11A; GPR85; G3BP2; PLG; VPS4A|
|ubiquitin conjugating enzyme activity||UBE2E2; UBE2D1; UBE2A; UBE2Z; UBE2C; UBE2V1; UBE2D2A; UBE2Q1; UBE2QL1; UBE2H|
|ubiquitin protein ligase activity||SIAH1; C18orf25; PRPF19; ZSWIM2; ASB4; CDC34A; ZNRF2; CDC42; RNF7; TRAF6|
|ubiquitin protein ligase binding||GABARAPL2; SLC22A18; UBE2L3; TRIM37; RPA2; RPA3; RANGAP1; UQCRC1; CUL5; TRIM28|
ube2v2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ube2v2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ube2v2.
UBE2N; UBC35; EIF1B; TRAF6; EGFR; RNF144A; USP14; XIAP; MKRN3; SNTA1; RIF1; DZIP3; SIAH1; ZNRF1; MALSU1; IGSF21