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Official Full Name ubiquitin protein ligase E3B
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family. The encoded protein may interact with other proteins and play a role in stress response. Alternatively spliced transcript variants encoding the same protein isoform have been identified for this gene.
Synonyms UBE3B; ubiquitin protein ligase E3B; ubiquitin-protein ligase E3B; MGC131858; MGC78388; AI449831; AU020130; FLJ45294; OTTHUMP00000240552; OTTHUMP00000240554; OTTHUMP00000240555; OTTHUMP00000240558
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE3B-720HCL Recombinant Human UBE3B lysate HEK293 N/A
    Mouse UBE3B-17739M Recombinant Mouse UBE3B Protein Mammalian Cell His
    Zebrafish UBE3B-6461Z Recombinant Zebrafish UBE3B Mammalian Cell His

    ube3b involved in several pathways and played different roles in them. We selected most pathways ube3b participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ube3b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis UBE2L3A; UBOX5; UBE3C; UBE2Q2; UBE4A; MGRN1B; CDH1-A; SOCS3; FBXW11B; UBE2E2

    ube3b has several biochemical functions, for example, ligase activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ube3b itself. We selected most functions ube3b had, and list some proteins which have the same functions with ube3b. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity RNF125; RNF111; SH3RF1; LTN1; HECW2; PIAS2; BRCA1; TRIM32; NEDD4; UFL1
    ubiquitin protein ligase activity DZIP3; UBE2B; HECTD2; MSL2A; RNF180; CCNB1IP1; RNF121; ITCH; RBX1; TRIM72

    ube3b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ube3b here. Most of them are supplied by our site. Hope this information will be useful for your research of ube3b.

    SHFM1; IQCB1; Oxnad1

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