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Official Full Name ubiquitin-conjugating enzyme E2M
Background Similar to ubiquitin, Nedd8 signals to target proteins through an enzymatic cascade composed of Nedd8-specific E1 (activating)- and E2 (conjugating)-enzymes. The E2 ligase specific for Nedd8 is Ubc12. Ubc12 forms a heterodimeric conjugate with NEDD8 in or
Synonyms UBE2M; ubiquitin-conjugating enzyme E2M; ubiquitin conjugating enzyme E2M (homologous to yeast UBC12) , ubiquitin conjugating enzyme E2M (UBC12 homolog, yeast); NEDD8-conjugating enzyme Ubc12; hUbc12; UBC12; yeast UBC12 homolog; NEDD8 protein ligase; NED
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2M-001H Recombinant Human UBE2M protein E.coli N/A
    Human UBE2M-05H Recombinant Human Ubiquitin Conjugating Enzyme 12, His6-Tagged E.coli His
    Human UBE2M-135H Recombinant Human UBE2M, His-tagged E.coli His
    Human UBE2M-1501H Recombinant Human Ubiquitin-Conjugating Enzyme E2M, His-tagged Human His
    Human UBE2M-567HCL Recombinant Human UBE2M 293 Cell Lysate HEK293 N/A
    Human UBE2M-6849H Recombinant Human Ubiquitin-Conjugating Enzyme E2M, His-tagged E.coli His
    Human UBE2M-857H Recombinant Human UBE2M, None tagged E.coli N/A
    Rhesus Macaque UBE2M-5065R Recombinant Rhesus monkey UBE2M Protein, His-tagged Mammalian Cell His

    ube2m involved in several pathways and played different roles in them. We selected most pathways ube2m participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ube2m were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis UBE4B; WWP2; FZR1; CUL3B; UBA6; PIAS4B; CUL1A; UBE2E2; UBE2Q1; DET1

    ube2m has several biochemical functions, for example, ATP binding, NEDD8 transferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ube2m itself. We selected most functions ube2m had, and list some proteins which have the same functions with ube2m. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding HIPK3A; MST1R; MAP3K15; P2RX7; OASL2; VPS4A; SLC27A2; VARS2; TTN; SKIV2L2
    NEDD8 transferase activity RBX1; RNF7; UBE2F; UBE2M
    protein binding MLLT10; LAIR1; STYK1; PPP1R13L; MAX; MAP4K1; TBX5; TEX13A; FBXL19; JAG2
    ribosomal S6-glutamic acid ligase activity HERC2; DTX1; UBR1; TRIM41; ZNRF3; MUL1A; RFWD2; MARCH9; SIAH1A; MYLIPB
    NOT ubiquitin protein ligase activity UBE2IA; UBE2IB; UBE2F; VHLL; UBE2I; UBE2M
    NOT ubiquitin protein ligase binding UBE2F; UBE2I; UBE2IB; UBE2M; UBE2IA
    ubiquitin-protein transferase activity UBE2D1; ARIH1; RNF43; WWP1; RNF6; NSMCE1; IRAK1; RNF10; TRIM33; ITCH

    ube2m has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ube2m here. Most of them are supplied by our site. Hope this information will be useful for your research of ube2m.

    CUL1; NEDD8; UBA3; FBXO11; CUL5; 51473135; PRKAR1A; MCC; CDK2

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