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UBE2N

  • Official Full Name

    ubiquitin-conjugating enzyme E2N

  • Overview

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived;proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or;E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the;E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication;repair.
  • Synonyms

    UBE2N; ubiquitin-conjugating enzyme E2N; ubiquitin conjugating enzyme E2N (homologous to yeast UBC13) , ubiquitin conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2 N; MGC8489; UBC13; UbcH ben; yeast UBC13 homolog; ubiquitin-p;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UBE2N-650H Active Recombinant Human UBE2N Protein, His-tagged E.coli His 2-end
Human UBE2N-136H Recombinant Human UBE2N E.coli N/A
Human UBE2N-3540H Recombinant Human UBE2N, GST-tagged E.coli GST 0-148aa
Human UBE2N-62H Recombinant Human UBE2N, His-tagged E.coli His
Human UBE2N-238H Recombinant Human UBE2N, His-tagged E.coli His
Human UBE2N-566HCL Recombinant Human UBE2N 293 Cell Lysate HEK293 N/A
Human UBE2N-1263H Recombinant Human UBE2N Protein (A2-I152), Tag Free Insect Cell No tag A2-I152
Human UBE2N-1221H Recombinant Human UBE2N Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UBE2N-1264H Recombinant Human UBE2N Protein (A2-I152), His/Strep tagged Insect Cell His/Strep A2-I152
Mouse Ube2n-6794M Recombinant Mouse Ube2n Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat UBE2N-6403R Recombinant Rat UBE2N Protein Mammalian Cell His
Rat UBE2N-6059R-B Recombinant Rat UBE2N Protein Pre-coupled Magnetic Beads HEK293
Rat UBE2N-6059R Recombinant Rat UBE2N Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey UBE2N-1075C Recombinant Cynomolgus UBE2N Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey UBE2N-818C Recombinant Cynomolgus Monkey UBE2N Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey UBE2N-818C-B Recombinant Cynomolgus Monkey UBE2N Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque UBE2N-5066R Recombinant Rhesus monkey UBE2N Protein, His-tagged Mammalian Cell His
Rhesus Macaque UBE2N-4879R Recombinant Rhesus Macaque UBE2N Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque UBE2N-4879R-B Recombinant Rhesus Macaque UBE2N Protein Pre-coupled Magnetic Beads HEK293
Chicken UBE2N-2038C Recombinant Chicken UBE2N Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

UBE2N involved in several pathways and played different roles in them. We selected most pathways UBE2N participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2N were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisWWP2;UBE2G2;KEAP1B;CDH1-A;HERC4;HERC3;CUL4A;UBA3;ANAPC1

UBE2N has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2N itself. We selected most functions UBE2N had, and list some proteins which have the same functions with UBE2N. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCDC42BPA;MAPK14;MCMDC2;MYO1D;CAMKK1;NEK3;HUNK;FPGS;SRPK1A
poly(A) RNA bindingHNRNPH2;DMGDH;EIF3C;SFPQ;PTCD3;IGF2BP2;G3BP1;PLEC;PTCD2
protein bindingMYO5A;IRF8;BRAF;COMMD3;BIRC2;ATP2C2;MYF5;TRIM39;CELSR1
ubiquitin bindingUBAP1;OTUB1;KCNS1;USP16;HSPB1;SQSTM1;UBXN2B;NUP62;UBXN1
ubiquitin conjugating enzyme activityUBE2D1;UBE2D3;UBE2N;UBE2O;UBE2A;UBE2G2;UBE2E2;UBE2Q2;UBE2C
ubiquitin protein ligase activityHUWE1;RBX1;RNF13;HECTD2;TRIM71;ITCHA;RNF144B;MYLIP;ARIH2
ubiquitin protein ligase bindingRANGAP1;DTX1;JKAMP;RAD18;UCHL1;RPA3;CUL2;BAG5;UQCRC1
ubiquitin-protein transferase activityRNF220;RNF5;FBXL14B;MARCH2;MARCH5L;CBLL1;PEX12;MARCH4;CDC23

UBE2N has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2N here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2N.

UBE2V1; STUB1

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