Recombinant Human protein phosphatase 1, regulatory (inhibitor) subunit 11, His-tagged

• Cat.No.: PPP1R11-219H
• Product Overview: PPP1R11, 1-126aa, Human, His tag, E.coli

Specification

• Description: Protein phosphatase 1 regulatory subunit 11, also known as PPP1R11, is a 126 amino acid protein that is expressed in a variety of both adult and fetal tissues. PPP1R11 functions as an inhibitor of PP1 (protein phosphatase 1), specifically exhibiting a sensitivity toward the metal-independent and metal-dependent forms of PP1. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Recombinant human PPP1R11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT
• Molecular Mass: 16.3kDa (149aa), confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAEAGAG LSETVTETTV TVTTEPENRS LTIKLRKRKP EKKVEWTSDT VDNEHMGRRS SKCCCIYEKP RAFGESSTES DEEEEEGCGH THCVRGHRKG RRRATLGPTP TTPPQPPDPS QPPPGPMQH
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PPP1R11?protein phosphatase 1, regulatory (inhibitor) subunit 11 [?Homo sapiens?(human) ]
• Official Symbol: PPP1R11
• Synonyms: PPP1R11; HCGV; IPP3; HCG-V; TCTE5; TCTEX5; protein phosphatase 1, regulatory (inhibitor) subunit 11; protein phosphatase 1 regulatory subunit 11; HCG V; inhibitor-3; protein phosphatase inhibitor 3; t-complex-associated-testis-expressed 5; hemochromatosis candidate gene V protein; protein phosphatase 1, regulatory (inhibitor) subunit 11, isoform 1; NP_068778.1; EC 3.1.3.16
• Gene ID: 6992
• mRNA Refseq: NM_021959
• Protein Refseq: NP_068778
• MIM: 606670
• UniProt ID: O60927
• Chromosome Location: 6p21.3
• Function: protein binding; protein phosphatase inhibitor activity