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Official Full Name protein phosphatase 2, regulatory subunit B, alpha
Background The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.
Synonyms PPP2R5A; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform , protein phosphatase 2, regulatory subunit B, alpha isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; B56A; PR61A; 2A5A_HUMAN; MGC131915; PP2A B Subunit B Alpha Isoform; PP2A B Subunit B56 Alpha Isoform; PP2A B subunit isoform B-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A B Subunit PR61 Alpha Isoform; PP2A B Subunit R5 Alpha Isoform; PR61alpha; Protein phosphatase 2 regulatory subunit B (B56) alpha isoform; Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform; OTTHUMP00000034891; PP2A, B subunit, B alpha isoform; PP2A, B subunit, R5 alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; protein phosphatase 2, regulatory subunit B, alpha isoform; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP2R5A-1404HCL Recombinant Human PPP2R5A cell lysate N/A
    Human PPP2R5A-1919H Recombinant Human PPP2R5A, GST-tagged E.coli GST
    Human PPP2R5A-31104TH Recombinant Human PPP2R5A Wheat Germ N/A
    Mouse PPP2R5A-13261M Recombinant Mouse PPP2R5A Protein Mammalian Cell His
    Rhesus Macaque PPP2R5A-3574R Recombinant Rhesus monkey PPP2R5A Protein, His-tagged Mammalian Cell His

    ppp2r5a involved in several pathways and played different roles in them. We selected most pathways ppp2r5a participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ppp2r5a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway PPP2R2CA; WDR33; UPF3B; ETF1B; PABPC1B; PPP2R5B; MSI2A; PABPN1; CASC3; PAPOLB
    Sphingolipid signaling pathway FCER1A; BAX; MS4A2; CERS5; MAP2K1; LASS4; MAPK8; PLD2; HRAS; MAPK1
    Oocyte meiosis PPP3R1; ITPR1; PPP2R1A; PTTG1; PRKACB; MOS; CAMK2D; CALM1; FBXW11; RBX1
    PIK-Akt signaling pathway TSC1; COL4A1; GNG13; TP53; EIF4E1B; IFNA2; GNG11; PPP2R5E; GNG2; TLR2
    AMPK signaling pathway PRKAA1; PPP2R5A; AKT1; ADIPOR1; GYS2; CAB39L; PCK2; RPS6KB1; INS1; CRTC2
    Adrenergic signaling in cardiomyocytes PPP2R5EA; PIK3R3B; TNNI3; TMEM8C; CACNG7A; PRKACAB; CAMK2G1; CREB1A; TNNC1; SCN1B
    Dopaminergic synapse ARRB2; CREB3L4; GNAI1; CALM1; PPP2R3A; GNAQ; GNG10; KIF5B; GNAO1; PRKACG

    ppp2r5a has several biochemical functions, for example, kinase binding, protein binding, protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ppp2r5a itself. We selected most functions ppp2r5a had, and list some proteins which have the same functions with ppp2r5a. You can find most of the proteins on our site.

    Function Related Protein
    kinase binding DUSP12; PER1; RB1; WWC2; PRPSAP1; SP100; DLG3; PTPN22; PFKFB1; RASGRP3
    protein binding ORC4L; PEX14; RBM44; AMOTL2A; CDK1; WHRN; EYA4; DCLRE1B; SILV; AGPAT4
    protein phosphatase type 2A regulator activity PPP2R4; ENSAA; PPP2R1B; PPP2R1A; PPP2R2D; ARPP19; PPP2R5CB; PPP2R2A; PPP2R3A; PPP2R5EB

    ppp2r5a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ppp2r5a here. Most of them are supplied by our site. Hope this information will be useful for your research of ppp2r5a.

    PPP2CA; PPP2R1A; PPP2R1B; Ppp2r1a; Sgol2; SGOL1; CHEK2

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